(2R,3R)-3-(Benzylcarbamoyl)oxirane-2-carboxylic acid

Base Information

Chemical Name:(2R,3R)-3-(Benzylcarbamoyl)oxirane-2-carboxylic acid
CAS No.:646532-96-9
Molecular Formula:C11H11NO4
Molecular Weight:221.213
Hs Code.:
DSSTox Substance ID:DTXSID30522361
Wikidata:Q82387554

Synonyms:(2R,3R)-3-(Benzylcarbamoyl)oxirane-2-carboxylic acid;646532-96-9;SCHEMBL6069261;DTXSID30522361

Suppliers and Price of (2R,3R)-3-(Benzylcarbamoyl)oxirane-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2R,3R)-3-(Benzylcarbamoyl)oxirane-2-carboxylic acid

Chemical Property:

XLogP3:0.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:221.06880783
Heavy Atom Count:16
Complexity:286

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CNC(=O)C2C(O2)C(=O)O
Isomeric SMILES:C1=CC=C(C=C1)CNC(=O)[C@H]2[C@@H](O2)C(=O)O

Technology Process of (2R,3R)-3-(Benzylcarbamoyl)oxirane-2-carboxylic acid

There total 2 articles about (2R,3R)-3-(Benzylcarbamoyl)oxirane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (2R,3R)-3-Benzylcarbamoyl-oxirane-2-carboxylic acid ethyl ester

: 646532-96-9
(2R,3R)-3-(3-benzylcarbamoyl)oxirane-2-carboxylic acid

Guidance literature:: With potassium hydroxide; In ethanol;
DOI:10.1021/jm0305016

Reference yield:

: 100-46-9
benzylamine

: 646532-96-9
(2R,3R)-3-(3-benzylcarbamoyl)oxirane-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1-hydroxybenzotriazole; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / CHCl₃ / 17 h / 0 - 20 °C

2: KOH / ethanol

With potassium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In ethanol; chloroform;
DOI:10.1021/jm0305016

Reference yield: 48.0%

: 646532-77-6
3-phenylpropanoyl-Val-Ala-NHNHCH₂COO-t-Bu

: 646532-96-9
(2R,3R)-3-(3-benzylcarbamoyl)oxirane-2-carboxylic acid

: 646532-07-2
(N-(3-benzylcarbamoyl-oxiranecarbonyl)-N'-{2-[3-methyl-2-(3-phenyl-propionylamino)-butyrylamino]-propionyl}-hydrazino)-acetic acid tert-butyl ester

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1021/jm0305016