5H-Pyrrolo[1,2-a]imidazole, 5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-6,7-dihydro-6,7-bis(phen ylmethoxy)-, (5R,6S,7S)-

Base Information

• Chemical Name: 5H-Pyrrolo[1,2-a]imidazole, 5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-6,7-dihydro-6,7-bis(phen ylmethoxy)-, (5R,6S,7S)-
• CAS No.: 647017-25-2
• Molecular Formula: C37H40N2O3Si
• Molecular Weight: 588.822
• Mol file: 647017-25-2.mol

Synonyms:

Chemical Property of 5H-Pyrrolo[1,2-a]imidazole, 5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-6,7-dihydro-6,7-bis(phen ylmethoxy)-, (5R,6S,7S)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5H-Pyrrolo[1,2-a]imidazole, 5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-6,7-dihydro-6,7-bis(phen ylmethoxy)-, (5R,6S,7S)-

There total 1 articles about 5H-Pyrrolo[1,2-a]imidazole, 5-[[[(1,1-dimethylethyl)diphenylsilyl]oxy]methyl]-6,7-dihydro-6,7-bis(phen ylmethoxy)-, (5R,6S,7S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

3,4-bis-benzyloxy-1-(tert-butyl-diphenyl-silanyloxy)-4-(1H-imidazol-2-yl)-butan-2-ol (647017-23-0) → 6,7-bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole (647017-25-2)

Guidance literature:

With pyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 0 - 20 ℃;

DOI:10.1016/S0968-0896(03)00402-4

Reference yield:

6,7-bis-benzyloxy-5-(tert-butyl-diphenyl-silanyloxymethyl)-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole (647017-25-2) → (6,7-bis-benzyloxy-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-5-yl)-methanol (647017-26-3)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/S0968-0896(03)00402-4

upstream raw materials:

3,4-bis-benzyloxy-1-(tert-butyl-diphenyl-silanyloxy)-4-(1H-imidazol-2-yl)-butan-2-ol

Downstream raw materials:

(6,7-bis-benzyloxy-6,7-dihydro-5H-pyrrolo[1,2-a]imidazol-5-yl)-methanol