Pentadecanoic acid, 3-[bis[(S)-(4-methylphenyl)sulfinyl]methyl]-2-methyl-, 2,6-dimethylphenyl ester, (2S,3R)-

Base Information

• Chemical Name: Pentadecanoic acid, 3-[bis[(S)-(4-methylphenyl)sulfinyl]methyl]-2-methyl-, 2,6-dimethylphenyl ester, (2S,3R)-
• CAS No.: 647835-05-0
• Molecular Formula: C39H54O4S2
• Molecular Weight: 650.987
• Mol file: 647835-05-0.mol

Synonyms:

Chemical Property of Pentadecanoic acid, 3-[bis[(S)-(4-methylphenyl)sulfinyl]methyl]-2-methyl-, 2,6-dimethylphenyl ester, (2S,3R)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pentadecanoic acid, 3-[bis[(S)-(4-methylphenyl)sulfinyl]methyl]-2-methyl-, 2,6-dimethylphenyl ester, (2S,3R)-

There total 1 articles about Pentadecanoic acid, 3-[bis[(S)-(4-methylphenyl)sulfinyl]methyl]-2-methyl-, 2,6-dimethylphenyl ester, (2S,3R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2,6-dimethylphenyl propionate (51233-80-8) + C28H40O2S2 → (2S,3R)-3-[Bis-((S)-toluene-4-sulfinyl)-methyl]-2-methyl-pentadecanoic acid 2,6-dimethyl-phenyl ester (647835-05-0)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

DOI:10.1002/anie.200352356

Reference yield:

(2S,3R)-3-[Bis-((S)-toluene-4-sulfinyl)-methyl]-2-methyl-pentadecanoic acid 2,6-dimethyl-phenyl ester (647835-05-0) → (2S,3R)-2-Methyl-3-p-tolylsulfanylcarbonyl-pentadecanoic acid 2,6-dimethyl-phenyl ester

Guidance literature:

With pyridine; trifluoroacetic anhydride;

DOI:10.1002/anie.200352356

Reference yield:

(2S,3R)-3-[Bis-((S)-toluene-4-sulfinyl)-methyl]-2-methyl-pentadecanoic acid 2,6-dimethyl-phenyl ester (647835-05-0) → (2S,3R)-(+)-roccellic acid (29838-46-8)

Guidance literature:

Multi-step reaction with 2 steps

1: trifluoroacetic anhydride; pyridine

2: LiOH; H₂O₂

With pyridine; lithium hydroxide; dihydrogen peroxide; trifluoroacetic anhydride; 1: Pummerer reaction;

DOI:10.1002/anie.200352356

upstream raw materials:

2,6-dimethylphenyl propionate

Downstream raw materials:

(2S,3R)-(+)-roccellic acid

Refernces