N-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methylbenzenesulfonamide

Base Information

Chemical Name:N-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methylbenzenesulfonamide
CAS No.:64880-90-6
Molecular Formula:C16H17NO4S
Molecular Weight:319.37500
Hs Code.:
DSSTox Substance ID:DTXSID70356985
Nikkaji Number:J1.645.058H
Wikidata:Q82136651
Mol file:64880-90-6.mol

Synonyms:N-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methylbenzenesulfonamide;64880-90-6;AN-970/40920815;N-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methylbenzenesulfonamide;N-[2-(Benzo[d][1,3]dioxol-5-yl)ethyl]-4-methylbenzenesulfonamide;DTXSID70356985

Suppliers and Price of N-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methylbenzenesulfonamide

Chemical Property:

PSA：73.01000
LogP:3.71640
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:319.08782920
Heavy Atom Count:22
Complexity:453

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NCCC2=CC3=C(C=C2)OCO3

Technology Process of N-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methylbenzenesulfonamide

There total 6 articles about N-[2-(1,3-benzodioxol-5-yl)ethyl]-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: N-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-4-methyl-N-tosylbenzenesulfonamide

: 64880-90-6
4′′-methyl-N-[(3,4-methylenedioxyphenyl)ethyl]benzenesulfonamide

Guidance literature:: With tetraethylammonium perchlorate; triethylamine; In dimethyl sulfoxide; at 20 ℃; for 9h; Electrolysis; Green chemistry;
DOI:10.1039/d1gc00317h

Reference yield: 81.0%

: 1484-85-1
3,4-methylenedioxyphenylethylamine

: 98-59-9
p-toluenesulfonyl chloride

: 64880-90-6
4′′-methyl-N-[(3,4-methylenedioxyphenyl)ethyl]benzenesulfonamide

Guidance literature:: With triethylamine; In tetrahydrofuran; for 12h;

Reference yield:

: 120-57-0,30024-74-9
piperonal

: 64880-90-6
4′′-methyl-N-[(3,4-methylenedioxyphenyl)ethyl]benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium acetate / toluene / 18 h / Inert atmosphere; Reflux

2: sodium tetrahydroborate; boron trifluoride diethyl etherate / tetrahydrofuran / 6.5 h / Inert atmosphere; Reflux

3: dichloromethane / 24.5 h / 0 - 20 °C / Inert atmosphere

With sodium tetrahydroborate; boron trifluoride diethyl etherate; ammonium acetate; In tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/acs.joc.8b02888