4-(MORPHOLINE-4-SULFONYL)-BENZOIC ACID

Base Information

• Chemical Name: 4-(MORPHOLINE-4-SULFONYL)-BENZOIC ACID
• CAS No.: 10252-82-1
• Molecular Formula: C11H13 N O5 S
• Molecular Weight: 271.294
• Hs Code.: 2934999090
• Mol file: 10252-82-1.mol

Synonyms:Benzoicacid, p-(morpholinosulfonyl)- (6CI,7CI,8CI); 4-(4-Morpholinylsulfonyl)benzoicacid; 4-(Morpholine-4-sulfonyl)benzoic acid

Chemical Property of 4-(MORPHOLINE-4-SULFONYL)-BENZOIC ACID

Chemical Property:

• Vapor Pressure: 3.75E-10mmHg at 25°C
• Boiling Point: 483.3°C at 760 mmHg
• Flash Point: 246.1°C
• PSA: 92.29000
• LogP: 1.42440
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

4-(Morpholin-4-ylsulfonyl)benzoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(MORPHOLINE-4-SULFONYL)-BENZOIC ACID

There total 3 articles about 4-(MORPHOLINE-4-SULFONYL)-BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.2%

→ 4-(morpholine-4-sulfonyl)-benzoic acid (10252-82-1)

Guidance literature:

With water; sodium hydroxide; In N,N-dimethyl-formamide; at 80 ℃; for 4h;

Reference yield: 93.0%

4-(morpholine-4-sulfonyl)benzoic acid methyl ester (332413-01-1) → 4-(morpholine-4-sulfonyl)-benzoic acid (10252-82-1)

Guidance literature:

With lithium hydroxide monohydrate; In methanol; water; at 20 ℃; for 2h;

DOI:10.1016/j.ejmech.2022.114145

Reference yield: 81.0%

morpholine (110-91-8,99108-56-2) + p-carboxyphenylsulfonyl chloride (10130-89-9) → 4-(morpholine-4-sulfonyl)-benzoic acid (10252-82-1)

Guidance literature:

In dichloromethane; at 20 ℃; for 2h;

upstream raw materials:

morpholine

p-carboxyphenylsulfonyl chloride

4-(morpholine-4-sulfonyl)benzoic acid methyl ester

Downstream raw materials:

4-(morpholine-4-sulfonyl)-benzoyl chloride

4-(morpholinosulfonyl)benzohydrazide

(E)-N'-(1-(5-chloro-2-hydroxyphenyl)ethylidene)-4-(morpholinosulfonyl)benzohydrazide

4-(morpholine-4-sulfonyl)benzoic acid methyl ester