4-Methoxy-1h-pyrrole-2-carboxylic acid

Base Information

Chemical Name:4-Methoxy-1h-pyrrole-2-carboxylic acid
CAS No.:90724-66-6
Molecular Formula:C₆H₇NO₃
Molecular Weight:141.126
Hs Code.:
NSC Number:134456
DSSTox Substance ID:DTXSID30300040
Wikidata:Q82042814

Synonyms:4-methoxy-1h-pyrrole-2-carboxylic acid;90724-66-6;MFCD19217443;NSC134456;SCHEMBL5173332;DTXSID30300040;AC8161;AKOS006348939;4-Methoxy-1H-pyrrole-2-carboxylicAcid;NSC-134456;SB63573;SY247648;CS-0459448

Suppliers and Price of 4-Methoxy-1h-pyrrole-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 4-Methoxy-1h-pyrrole-2-carboxylic acid

Chemical Property:

Vapor Pressure:4.49E-06mmHg at 25°C
Boiling Point:368.3°C at 760 mmHg
Flash Point:176.5°C
Density:1.353g/cm³
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:141.042593085
Heavy Atom Count:10
Complexity:137

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CNC(=C1)C(=O)O

Technology Process of 4-Methoxy-1h-pyrrole-2-carboxylic acid

There total 3 articles about 4-Methoxy-1h-pyrrole-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 16176-31-1
4-methoxy-pyrrole-1,2-dicarboxylic acid diethyl ester

: 90724-66-6
4-methoxy-2-pyrrolecarboxylic acid

Guidance literature:: With sodium hydroxide;

Reference yield:

: 41263-42-7
rac-4-oxo-1,2-pyrrolidinedicarboxylic acid diethyl ester

: 90724-66-6
4-methoxy-2-pyrrolecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: HCl; methanol / Erhitzen bis auf 200grad, Behandeln des Reaktionsprodukts mit N-Brom-succinimid und Triaethylamin in CCl₄

2: aqueous methanol. NaOH

With hydrogenchloride; methanol; sodium hydroxide;