4-Pyridinecarboxaldehyde, 3-(methylthio)- (9CI)

Base Information

Chemical Name:4-Pyridinecarboxaldehyde, 3-(methylthio)- (9CI)
CAS No.:650628-88-9
Molecular Formula:C7H7NOS
Molecular Weight:153.20200
Hs Code.:
Mol file:650628-88-9.mol

Synonyms:4-Pyridinecarboxaldehyde,3-(methylthio);3-methylthioisonicotinaldehyde;

Suppliers and Price of 4-Pyridinecarboxaldehyde, 3-(methylthio)- (9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-Pyridinecarboxaldehyde, 3-(methylthio)- (9CI)

Chemical Property:

PSA：55.26000
LogP:1.61600

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4-Pyridinecarboxaldehyde, 3-(methylthio)- (9CI)

There total 2 articles about 4-Pyridinecarboxaldehyde, 3-(methylthio)- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 70201-43-3
3-bromo-pyridine-4-carbaldehyde

: 5188-07-8
sodium thiomethoxide

: 650628-88-9
3-methylthioisonicotinaldehyde

Guidance literature:: In methanol;
DOI:10.1055/s-2005-872165

Reference yield:

: 13600-45-8
3-methylthio-4-cyanopyridine

: 650628-88-9
3-methylthioisonicotinaldehyde

Guidance literature:: 3-methylthio-4-cyanopyridine; With diisobutylaluminium hydride; In tetrahydrofuran; toluene; for 2h;

With sulfuric acid; water; In tetrahydrofuran; toluene; for 16h;

Reference yield:

: 650628-88-9
3-methylthioisonicotinaldehyde

: 871583-22-1
methyl 4-(methylthio)-1H-pyrrolo[2,3-c]pyridine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 44 percent / NaOMe / methanol / -10 - 0 °C

2: 51 percent / decahydronaphthalene / 0.17 h / 191 °C

With sodium methylate; In methanol; decalin; 2: Hemetsberger-Knittel reaction;
DOI:10.1055/s-2005-872165