Furan, tetrahydro-2-[(1R)-1-iodo-4-(triphenylmethoxy)butyl]-, (2R)-

Base Information

Chemical Name:Furan, tetrahydro-2-[(1R)-1-iodo-4-(triphenylmethoxy)butyl]-, (2R)-
CAS No.:651057-16-8
Molecular Formula:C27H29IO2
Molecular Weight:512.431
Hs Code.:
DSSTox Substance ID:DTXSID00458946
Nikkaji Number:J1.990.684A
Wikidata:Q82282518

Synonyms:651057-16-8;Furan, tetrahydro-2-[(1R)-1-iodo-4-(triphenylmethoxy)butyl]-, (2R)-;DTXSID00458946;2beta-[(R)-1-Iodo-4-(trityloxy)butyl]tetrahydrofuran;(R)-2-((R)-1-Iodo-4-(trityloxy)butyl)tetrahydrofuran

Suppliers and Price of Furan, tetrahydro-2-[(1R)-1-iodo-4-(triphenylmethoxy)butyl]-, (2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Furan, tetrahydro-2-[(1R)-1-iodo-4-(triphenylmethoxy)butyl]-, (2R)-

Chemical Property:

XLogP3:6.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:9
Exact Mass:512.12123
Heavy Atom Count:30
Complexity:432

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(OC1)C(CCCOC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)I
Isomeric SMILES:C1C[C@@H](OC1)[C@@H](CCCOC(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)I

Technology Process of Furan, tetrahydro-2-[(1R)-1-iodo-4-(triphenylmethoxy)butyl]-, (2R)-

There total 1 articles about Furan, tetrahydro-2-[(1R)-1-iodo-4-(triphenylmethoxy)butyl]-, (2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 528840-86-0
(Z)-8-Trityloxy-oct-4-en-1-ol

: (S)-2-((S)-1-Iodo-4-trityloxy-butyl)-tetrahydro-furan

: 651057-16-8
(R)-2-((R)-1-iodo-4-(trityloxy)butyl)tetrahydrofuran

Guidance literature:: With N-chloro-succinimide; (R,R)-(-)-N,N′-bis(3,5-di-tertbutylsalicylidene)-1,2-cyclohexanediaminocobalt(II); iodine; In toluene; at -78 ℃; for 20h; Title compound not separated from byproducts;
DOI:10.1021/ja0369921

Reference yield:

: 651057-16-8
(R)-2-((R)-1-iodo-4-(trityloxy)butyl)tetrahydrofuran

: Benzoic acid (S)-4-(tetrahydro-furan-2-yl)-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: aq. HCl / methanol / 1 h / 20 °C

2: DMAP; triethylamine / CH₂Cl₂ / 0.5 h / 20 °C

3: n-Bu₃SnH; Et₃B / tetrahydrofuran / 2 h / -78 °C

With hydrogenchloride; dmap; triethyl borane; tri-n-butyl-tin hydride; triethylamine; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/ja0369921

Reference yield:

: 651057-16-8
(R)-2-((R)-1-iodo-4-(trityloxy)butyl)tetrahydrofuran

: Benzoic acid (R)-4-iodo-4-(R)-tetrahydro-furan-2-yl-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: aq. HCl / methanol / 1 h / 20 °C

2: DMAP; triethylamine / CH₂Cl₂ / 0.5 h / 20 °C

With hydrogenchloride; dmap; triethylamine; In methanol; dichloromethane;
DOI:10.1021/ja0369921