Methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate

Base Information

Chemical Name:Methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate
CAS No.:65117-76-2
Molecular Formula:C18H15NO2
Molecular Weight:277.323
Hs Code.:
DSSTox Substance ID:DTXSID00495250
Nikkaji Number:J2.411.264K
Wikidata:Q82343231

Synonyms:Methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate;65117-76-2;DTXSID00495250

Suppliers and Price of Methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:277.110278721
Heavy Atom Count:21
Complexity:345

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=CC(=C(N1)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of Methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate

There total 13 articles about Methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 116340-87-5
2-Azido-5,5-diphenyl-2,4-pentadiensaeuremethylester

: 65117-76-2
methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate

Guidance literature:: With meso-tetraphenylporphyrin iron(III) chloride; zinc; In chlorobenzene; at 80 ℃; for 4h; Inert atmosphere; Glovebox;
DOI:10.1002/anie.202014950

Reference yield: 91.0%

: 35356-70-8
Methyl 2-acetamidoacrylate

: 501-65-5
diphenyl acetylene

: 65117-76-2
methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate

Guidance literature:: With silver hexafluoroantimonate; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; copper(II) acetate monohydrate; In methanol; dichloromethane; at 100 ℃; for 12h; regioselective reaction; Inert atmosphere;
DOI:10.1021/ol303159h

Reference yield: 89.0%

: 35356-70-8
Methyl 2-acetamidoacrylate

: 501-65-5
diphenyl acetylene

: 1259284-14-4
1-acetyl-4,5-diphenyl-1H-pyrrole-2-carboxylic acid methyl ester

: 65117-76-2
methyl 4,5-diphenyl-1H-pyrrole-2-carboxylate

Guidance literature:: With silver hexafluoroantimonate; [RhCl₂(p-cymene)]2; copper(II) acetate monohydrate; In methanol; 1,2-dichloro-ethane; at 110 ℃; for 24h; Sealed tube; Inert atmosphere;
DOI:10.1055/s-0036-1591209