2,6-Dimethoxyterephthalic acid

Base Information

• Chemical Name: 2,6-Dimethoxyterephthalic acid
• CAS No.: 16849-69-7
• Molecular Formula: C10H10 O6
• Molecular Weight: 226.186
• Hs Code.: 2918990090
• European Community (EC) Number: 240-872-1
• DSSTox Substance ID: DTXSID80168571
• Nikkaji Number: J236.871D
• Wikidata: Q77484784
• Metabolomics Workbench ID: 110006
• Mol file: 16849-69-7.mol

Synonyms:2,6-dimethoxy terephthalic acid

Chemical Property of 2,6-Dimethoxyterephthalic acid

Chemical Property:

• Vapor Pressure: 3.17E-08mmHg at 25°C
• Boiling Point: 431.9°Cat760mmHg
• Flash Point: 173.6°C
• PSA: 93.06000
• Density: 1.391g/cm³
• LogP: 1.10020
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 226.04773803
• Heavy Atom Count: 16
• Complexity: 263

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1C(=O)O)OC)C(=O)O

Technology Process of 2,6-Dimethoxyterephthalic acid

There total 2 articles about 2,6-Dimethoxyterephthalic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethyl 2,6-dimethoxyterephthalate (16849-68-6) → 2,6-dimethoxyterephthalic acid (16849-69-7)

Guidance literature:

With potassium hydroxide;

Reference yield:

2,6-dimethoxy-4-methylbenzoic acid (20872-08-6) → 2,6-dimethoxyterephthalic acid (16849-69-7)

Guidance literature:

With alkaline permanganate;

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2,6-dimethoxyterephthalic acid (16849-69-7) → dimethyl 2,6-dimethoxyterephthalate (16849-68-6)

Guidance literature:

DOI:10.1248/cpb.11.1174

upstream raw materials:

2,6-dimethoxy-4-methylbenzoic acid

dimethyl 2,6-dimethoxyterephthalate

Downstream raw materials:

dimethyl 2,6-dimethoxyterephthalate