1H-Isoindol-1-one, 5-amino-2-(3,5-dimethylphenyl)-2,3-dihydro-

Base Information

Chemical Name:1H-Isoindol-1-one, 5-amino-2-(3,5-dimethylphenyl)-2,3-dihydro-
CAS No.:651733-87-8
Molecular Formula:C₁₆H₁₆N₂O
Molecular Weight:252.316
Hs Code.:
DSSTox Substance ID:DTXSID60477355
Nikkaji Number:J1.932.675F
Wikidata:Q82309811

Synonyms:651733-87-8;1H-Isoindol-1-one, 5-amino-2-(3,5-dimethylphenyl)-2,3-dihydro-;DTXSID60477355

Suppliers and Price of 1H-Isoindol-1-one, 5-amino-2-(3,5-dimethylphenyl)-2,3-dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1H-Isoindol-1-one, 5-amino-2-(3,5-dimethylphenyl)-2,3-dihydro-

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:252.126263138
Heavy Atom Count:19
Complexity:347

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1)N2CC3=C(C2=O)C=CC(=C3)N)C

Technology Process of 1H-Isoindol-1-one, 5-amino-2-(3,5-dimethylphenyl)-2,3-dihydro-

There total 3 articles about 1H-Isoindol-1-one, 5-amino-2-(3,5-dimethylphenyl)-2,3-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 651733-75-4
2-(3,5-dimethyl-phenyl)-5-nitro-isoindole-1,3-dione

: 651733-87-8
5-amino-2-(3,5-dimethyl-phenyl)-2,3-dihydro-isoindol-1-one

: 651733-84-5
6-amino-2-(3,5-dimethyl-phenyl)-2,3-dihydro-isoindol-1-one

Guidance literature:: With hydrogenchloride; tin; In ethanol; at 75 ℃; for 8h;
DOI:10.1248/cpb.51.1098

Reference yield:

: 5466-84-2
4-nitrophthalic anhydride

: 651733-87-8
5-amino-2-(3,5-dimethyl-phenyl)-2,3-dihydro-isoindol-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: AcOH / 24 h / Heating

2: 38 percent / Sn; aq. HCl / ethanol / 8 h / 75 °C

With hydrogenchloride; tin; acetic acid; In ethanol;
DOI:10.1248/cpb.51.1098

Reference yield:

: 108-69-0
3,5-dimethylaminoaniline

: 651733-87-8
5-amino-2-(3,5-dimethyl-phenyl)-2,3-dihydro-isoindol-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: AcOH / 24 h / Heating

2: 38 percent / Sn; aq. HCl / ethanol / 8 h / 75 °C

With hydrogenchloride; tin; acetic acid; In ethanol;
DOI:10.1248/cpb.51.1098