1H-Isoindol-5-amine, 2-(3,5-dimethylphenyl)-2,3-dihydro-

Base Information

Chemical Name:1H-Isoindol-5-amine, 2-(3,5-dimethylphenyl)-2,3-dihydro-
CAS No.:651733-97-0
Molecular Formula:C₁₆H₁₈N₂
Molecular Weight:238.332
Hs Code.:
DSSTox Substance ID:DTXSID40437558
Wikidata:Q82253079

Synonyms:651733-97-0;1H-Isoindol-5-amine, 2-(3,5-dimethylphenyl)-2,3-dihydro-;DTXSID40437558

Suppliers and Price of 1H-Isoindol-5-amine, 2-(3,5-dimethylphenyl)-2,3-dihydro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1H-Isoindol-5-amine, 2-(3,5-dimethylphenyl)-2,3-dihydro-

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:238.146998583
Heavy Atom Count:18
Complexity:281

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1)N2CC3=C(C2)C=C(C=C3)N)C

Technology Process of 1H-Isoindol-5-amine, 2-(3,5-dimethylphenyl)-2,3-dihydro-

There total 3 articles about 1H-Isoindol-5-amine, 2-(3,5-dimethylphenyl)-2,3-dihydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 651733-95-8
2-(3,5-dimethyl-phenyl)-5-nitro-2,3-dihydro-1H-isoindole

: 651733-97-0
2-(3,5-dimethyl-phenyl)-2,3-dihydro-1H-isoindol-5-ylamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; for 3h;
DOI:10.1248/cpb.51.1098

Reference yield:

: 108-69-0
3,5-dimethylaminoaniline

: 651733-97-0
2-(3,5-dimethyl-phenyl)-2,3-dihydro-1H-isoindol-5-ylamine

Guidance literature:: Multi-step reaction with 3 steps

1: AcOH / 24 h / Heating

2: 67 percent / borane / tetrahydrofuran / 16 h / Heating

3: H₂ / Pd/C / ethyl acetate / 3 h

With borane; hydrogen; acetic acid; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate;
DOI:10.1248/cpb.51.1098

Reference yield:

: 651733-75-4
2-(3,5-dimethyl-phenyl)-5-nitro-isoindole-1,3-dione

: 651733-97-0
2-(3,5-dimethyl-phenyl)-2,3-dihydro-1H-isoindol-5-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / borane / tetrahydrofuran / 16 h / Heating

2: H₂ / Pd/C / ethyl acetate / 3 h

With borane; hydrogen; palladium on activated charcoal; In tetrahydrofuran; ethyl acetate;
DOI:10.1248/cpb.51.1098