Methyl 2-fluoro-3,5-diMethoxybenzoate

Base Information

• Chemical Name: Methyl 2-fluoro-3,5-diMethoxybenzoate
• CAS No.: 651734-58-6
• Molecular Formula: C10H11FO4
• Molecular Weight: 214.193
• Hs Code.: 2918990090
• Mol file: 651734-58-6.mol

Synonyms:2-fluoro-3,5-dimethoxybenzoic acid methyl ester;Benzoic acid,2-fluoro-3,5-dimethoxy-,methyl ester;

Chemical Property of Methyl 2-fluoro-3,5-diMethoxybenzoate

Chemical Property:

• PSA: 44.76000
• LogP: 1.62950
• Storage Temp.: 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Methyl2-fluoro-3,5-dimethoxybenzoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 2-fluoro-3,5-diMethoxybenzoate

There total 2 articles about Methyl 2-fluoro-3,5-diMethoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

methyl 3,5-dimethoxybenzoate (2150-37-0) → methyl 2-fluoro-3,5-dimethoxybenzoate (651734-58-6)

Guidance literature:

With Selectfluor; In acetonitrile; at 0 - 20 ℃;

Reference yield:

methyl 3,5-dimethoxybenzoate (2150-37-0) → methyl 2,6-difluoro-3,5-dimethoxybenzoate (651734-55-3) + methyl 2-fluoro-3,5-dimethoxybenzoate (651734-58-6)

Guidance literature:

With Selectfluor; In acetonitrile; at 0 - 20 ℃;

Reference yield: 87.9%

methyl 2-fluoro-3,5-dimethoxybenzoate (651734-58-6) → C9H11FO3

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 25 ℃; for 0.5h; Cooling with ice;

upstream raw materials:

methyl 3,5-dimethoxybenzoate

Downstream raw materials:

methyl 2-chloro-6-fluoro-3,5-dimethoxybenzoate

2-fluoro-3,5-dimethoxy-benzoic acid

2-chloro-6-fluoro-3,5-dimethoxybenzoic acid

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