4-BENZYLTHIOMORPHOLINE 1,1-DIOXIDE

Base Information

• Chemical Name: 4-BENZYLTHIOMORPHOLINE 1,1-DIOXIDE
• CAS No.: 26475-66-1
• Molecular Formula: C11H15 N O2 S
• Molecular Weight: 225.312
• Hs Code.: 2934999090
• Mol file: 26475-66-1.mol

Synonyms:Thiomorpholine,4-benzyl-, 1,1-dioxide (7CI,8CI); NSC 255018

Chemical Property of 4-BENZYLTHIOMORPHOLINE 1,1-DIOXIDE

Chemical Property:

• Vapor Pressure: 1.54E-06mmHg at 25°C
• Melting Point: 85 °C
• Boiling Point: 397.9°Cat760mmHg
• PKA: 5.15±0.20(Predicted)
• Flash Point: 194.4°C
• PSA: 45.76000
• Density: 1.235g/cm³
• LogP: 1.93570
• Solubility.: soluble in Acetone

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Benzylthiomorpholine 1,1-Dioxide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi,Xn
• Statements: 22-36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BENZYLTHIOMORPHOLINE 1,1-DIOXIDE

There total 6 articles about 4-BENZYLTHIOMORPHOLINE 1,1-DIOXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Divinyl sulfone (77-77-0) + benzylamine (100-46-9) → 4-benzylthiomorpholine 1,1-dioxide (26475-66-1)

Guidance literature:

In water; isopropyl alcohol; for 1h; Heating;

DOI:10.1002/1099-0690(200301)2003:1<54::AID-EJOC54>3.0.CO;2-R

Reference yield: 98.0%

thiomorpholine 1,1-dioxide (39093-93-1) + benzyl alcohol (100-51-6,185532-71-2) → 4-benzylthiomorpholine 1,1-dioxide (26475-66-1)

Guidance literature:

With bis(triphenylphosphine)carbonylmonohydrate ruthenium dichloride; at 150 ℃; for 5h; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1039/d1ob00368b

Reference yield: 88.0%

4-benzylthiomorpholine 1,1-dioxide → 4-benzylthiomorpholine 1,1-dioxide (26475-66-1)

Guidance literature:

With Methyl phenyldiazoacetate; copper(II) bis(trifluoromethanesulfonate); In 1,2-dichloro-ethane; at 60 ℃; for 12h; Inert atmosphere; Sealed tube; Molecular sieve;

DOI:10.1039/c5cc01739d

upstream raw materials:

3-Sulfolene

benzylamine

Divinyl sulfone

4-benzyl-thiomorpholine

Downstream raw materials:

4-benzyl-thiomorpholine

4-Benzyl-4-methyl-1,1-dioxo-1λ⁶-thiomorpholin-4-ium; iodide

4-Allyl-4-benzyl-thiazonium-1,1-dioxid

Refernces

• 1、 -. "Application of bis(triphenylphosphine)carbonyl ruthenium dichloride monohydrate". Paragraph 0163-0165. . Retrieved 2021/07/10.
• 2、 -. "A sulfide oxidation method cheng Feng". Paragraph 0030-0033. . Retrieved 2018/03/01.