6-[(2-bromoacetyl)amino]-N-phenylhexanamide

Base Information

Chemical Name:6-[(2-bromoacetyl)amino]-N-phenylhexanamide
CAS No.:651767-99-6
Molecular Formula:C14H19BrN2O2
Molecular Weight:327.221
Hs Code.:
DSSTox Substance ID:DTXSID50432973
Nikkaji Number:J2.037.868I
Wikidata:Q82247119
ChEMBL ID:CHEMBL344920

Synonyms:6-[(2-bromoacetyl)amino]-N-phenylhexanamide;651767-99-6;CHEMBL344920;6-(2-Bromo-acetylamino)-hexanoic acid phenylamide;D02MQM;SCHEMBL3736839;DTXSID50432973;HWYLREOMBVUGJQ-UHFFFAOYSA-N;BDBM50222416;N-Phenyl-6-(bromoacetylamino)hexanamide;PD182687

Suppliers and Price of 6-[(2-bromoacetyl)amino]-N-phenylhexanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 6-[(2-bromoacetyl)amino]-N-phenylhexanamide

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:8
Exact Mass:326.06299
Heavy Atom Count:19
Complexity:279

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)NC(=O)CCCCCNC(=O)CBr

Technology Process of 6-[(2-bromoacetyl)amino]-N-phenylhexanamide

There total 13 articles about 6-[(2-bromoacetyl)amino]-N-phenylhexanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

: 115012-25-4
6-aminohexanoic acid phenylamide

: 598-21-0
2-Bromoacetyl bromide

: 651767-99-6
6-(bromoacetamido)-1-hexanoic acid anilide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 20 ℃; for 0.5h;
DOI:10.1021/jm049207j

Reference yield:

: 111-16-0
heptanedioic acid

: 651767-99-6
6-(bromoacetamido)-1-hexanoic acid anilide

Guidance literature:: Multi-step reaction with 4 steps

1.1: 49 percent / 1 h / 180 °C

2.1: triethylamine; diphenylphosphoryl azide / benzene / 1 h / Heating

2.2: 63 percent / benzene / 24 h / Heating

3.1: 96 percent / H₂ / Pd/C / methanol / 7 h / 20 °C

4.1: triethylamine / tetrahydrofuran / 1 h / 20 °C

With diphenylphosphoranyl azide; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; benzene;
DOI:10.1016/j.bmc.2005.04.002

Reference yield:

: 160777-08-2
7-oxo-7-(phenylamino)heptanoic acid

: 651767-99-6
6-(bromoacetamido)-1-hexanoic acid anilide

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine; diphenylphosphoryl azide / benzene / 1 h / Heating

1.2: 63 percent / benzene / 24 h / Heating

2.1: 96 percent / H₂ / Pd/C / methanol / 7 h / 20 °C

3.1: triethylamine / tetrahydrofuran / 1 h / 20 °C

With diphenylphosphoranyl azide; hydrogen; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; benzene;
DOI:10.1016/j.bmc.2005.04.002