3,7-Dimethyloct-6-ene-1,2,3-triol

Base Information

• Chemical Name: 3,7-Dimethyloct-6-ene-1,2,3-triol
• CAS No.: 65180-52-1
• Molecular Formula: C10H20O3
• DSSTox Substance ID: DTXSID80515465
• Nikkaji Number: J1.609.525G
• Mol file: 65180-52-1.mol

Synonyms:3,7-DIMETHYLOCT-6-ENE-1,2,3-TRIOL;65180-52-1;DTXSID80515465

Chemical Property of 3,7-Dimethyloct-6-ene-1,2,3-triol

Chemical Property:

• XLogP3: 0.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 188.14124450
• Heavy Atom Count: 13
• Complexity: 173

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=CCCC(C)(C(CO)O)O)C

Technology Process of 3,7-Dimethyloct-6-ene-1,2,3-triol

There total 1 articles about 3,7-Dimethyloct-6-ene-1,2,3-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Geraniol (106-24-1) → 3,7-dimethyl-oct-6-ene-1,2,3-triol (65180-52-1) + trans-3,7-Dimethyl-6,7-dihydroxy-2-octen-1-ol (154631-44-4,63955-78-2)

Guidance literature:

With AD-mix-α; osmium(VIII) oxide; In tetrahydrofuran; pyridine; water; butan-1-ol; Yield given. Yields of byproduct given; 0 deg C, 24 h;

DOI:10.1016/0040-4039(93)85077-A

Reference yield:

3,7-dimethyl-6-octene-1,2,3-triol (65180-52-1) + tert-butylchlorodiphenylsilane (58479-61-1) → (2R,3S)-1-(tert-butyldiphenylsilyloxy)-3,7-dimethyl-6-octene-2,3-diol (1109222-01-6) + (2S,3R)-1-(tert-butyldiphenylsilyloxy)-3,7-dimethyl-6-octene-2,3-diol (1609197-51-4)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 20 ℃; for 0.0833333h; Overall yield = 92 mg;

DOI:10.3762/bjoc.9.273

Reference yield:

3,7-dimethyl-6-octene-1,2,3-triol (65180-52-1) + tert-butylchlorodiphenylsilane (58479-61-1) → (2S,3S)-1-(tert-butyldiphenylsilyloxy)-3,7-dimethyl-6-octene-2,3-diol (859436-74-1) + (2R,3R)-1-(tert-butyldiphenylsilyloxy)-3,7-dimethyl-6-octene-2,3-diol (859436-76-3)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 20 ℃; for 0.0833333h; Overall yield = 92 %;

DOI:10.3762/bjoc.9.273

upstream raw materials:

Geraniol

Downstream raw materials:

1-(tert-butyl-diphenyl-silanyloxy)-3,7-dimethyl-oct-6-ene-2,3-diol

1-(tert-butyl-diphenyl-silanyloxy)-3-hydroxy-3,7-dimethyl-oct-6-en-2-one

(2R,3S)-1-(tert-butyldiphenylsilyloxy)-3,7-dimethyl-6-octene-2,3-diol

(2S,3R)-1-(tert-butyldiphenylsilyloxy)-3,7-dimethyl-6-octene-2,3-diol