tert-Butyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate

Base Information

Chemical Name:tert-Butyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate
CAS No.:652153-62-3
Molecular Formula:C13H17NO4
Molecular Weight:251.27800
Hs Code.:2932999099
DSSTox Substance ID:DTXSID40463453
Nikkaji Number:J2.858.440G
Wikidata:Q82288334
Mol file:652153-62-3.mol

Synonyms:tert-Butyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate;652153-62-3;tert-butyl N-(2,3-dihydro-1,4-benzodioxin-6-yl)carbamate;SCHEMBL8342099;DTXSID40463453;tert-Butyl(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate;AKOS014476258;FT-0717824;A867705

Suppliers and Price of tert-Butyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
tert-Butyl(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate 95+%
100g
$ 469.00

Chemenu
tert-Butyl(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate 95%
100g
$ 443.00

American Custom Chemicals Corporation
TERT-BUTYL-(2,3-DIHYDROBENZO[B][1,4]DIOXIN-6-YL)CARBAMATE 95.00%
5MG
$ 500.37

Total 7 raw suppliers

Chemical Property of tert-Butyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate

Chemical Property:

PSA：60.28000
LogP:2.81840
Storage Temp.:2-8°C
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:251.11575802
Heavy Atom Count:18
Complexity:300

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC2=C(C=C1)OCCO2

Technology Process of tert-Butyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate

There total 2 articles about tert-Butyl (2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: tert-butyl 2,3-dihydrobenzo[b][1,4]dioxin-6-yl(3-perfluorooctylpropoxy)carbamate

: 652153-62-3
(2,3-dihydrobenzo[1,4]dioxin-6-yl)carbamic acid tert-butyl ester

Guidance literature:: With methanol; tris(propionitrile)tricarbonylmolybdenum⁽⁰⁾; at 130 ℃; for 0.25h; chemoselective reaction; Microwave irradiation; Inert atmosphere;
DOI:10.1002/ejoc.201000367

Reference yield: 71.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 22013-33-8
6-amino-3,4-benzodioxane

: 652153-62-3
(2,3-dihydrobenzo[1,4]dioxin-6-yl)carbamic acid tert-butyl ester

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 72h;
DOI:10.1021/jm040214h

Reference yield:

: 652153-62-3
(2,3-dihydrobenzo[1,4]dioxin-6-yl)carbamic acid tert-butyl ester

: methyl 2-(7-((tert-butoxycarbonyl)((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)amino)-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C

1.2: 0 - 20 °C

2.1: norborn-2-ene; silver(I) acetate; palladium diacetate; N-(2-hydroxypyridin-3-yl)acetamide / 1,2-dichloro-ethane / 24 h / 100 °C

With norborn-2-ene; N-(2-hydroxypyridin-3-yl)acetamide; silver(I) acetate; palladium diacetate; sodium hydride; In 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1021/jacs.6b04966