2-(4-chloro-2-nitrophenyl)-1H-indole

Base Information

Chemical Name:2-(4-chloro-2-nitrophenyl)-1H-indole
CAS No.:65287-40-3
Molecular Formula:C14H9ClN2O2
Molecular Weight:272.691
Hs Code.:
DSSTox Substance ID:DTXSID90347592
Wikidata:Q82121674

Synonyms:2-(4-chloro-2-nitrophenyl)-1H-indole;65287-40-3;2-[4-Chloro-2-nitrophenyl]-1H-indole;DTXSID90347592

Suppliers and Price of 2-(4-chloro-2-nitrophenyl)-1H-indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-(4-chloro-2-nitrophenyl)-1H-indole

Chemical Property:

XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:272.0352552
Heavy Atom Count:19
Complexity:347

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C=C(N2)C3=C(C=C(C=C3)Cl)[N+](=O)[O-]

Technology Process of 2-(4-chloro-2-nitrophenyl)-1H-indole

There total 5 articles about 2-(4-chloro-2-nitrophenyl)-1H-indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 23082-51-1
4'-chloro-2'-nitroacetophenone

: 65287-40-3
2-(4-chloro-2-nitrophenyl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / AcOH / ethanol / 8 h / Heating

2: 34 percent / polyphosphoric acid (PPA) / 1 h / 105 °C

With PPA; Polyphosphoric acid (PPA); acetic acid; In ethanol;
DOI:10.1016/0223-5234(93)90036-E

Reference yield:

: [2-(4-Chloro-2-nitro-benzoylamino)-benzyl]-triphenyl-phosphonium

: 65287-40-3
2-(4-chloro-2-nitrophenyl)-1H-indole

Guidance literature:: With potassium tert-butylate; In N,N-dimethyl-formamide; toluene; for 1h; Yield given; Heating;

Reference yield:

: 41995-04-4
4-chloro-2-nitro-benzoyl chloride

: 65287-40-3
2-(4-chloro-2-nitrophenyl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / CH₂Cl₂ / 0.5 h / Heating

2: t-BuOK / toluene; dimethylformamide / 1 h / Heating

With pyridine; potassium tert-butylate; In dichloromethane; N,N-dimethyl-formamide; toluene;