1-Hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine

Base Information

Chemical Name:1-Hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine
CAS No.:88587-94-4
Molecular Formula:C₄₀H₈₂NO₇P
Molecular Weight:720.067
Hs Code.:
DSSTox Substance ID:DTXSID90237161
Wikidata:Q27140112
Metabolomics Workbench ID:14664
Mol file:88587-94-4.mol

Synonyms:1-hexadecyl-2-palmitoyl-sn-glycero-3-phosphocholine;1-O-DPPC;HD-P-PC

Suppliers and Price of 1-Hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-HEXADECYL-2-PALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 95.00%
5MG
$ 500.50

Total 0 raw suppliers

Chemical Property of 1-Hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine

Chemical Property:

PSA：103.93000
LogP:12.15540
XLogP3:13.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:40
Exact Mass:719.58289095
Heavy Atom Count:49
Complexity:753

Purity/Quality:: 1-HEXADECYL-2-PALMITOYL-SN-GLYCERO-3-PHOSPHORYLCHOLINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Lipids -> Unambiguous Lipids
Canonical SMILES:CCCCCCCCCCCCCCCCOCC(COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC
Isomeric SMILES:CCCCCCCCCCCCCCCCOC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCCCCCCCCCC

Technology Process of 1-Hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine

There total 12 articles about 1-Hexadecyl-2-hexadecanoyl-sn-glycero-3-phosphocholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 623-65-4
palmitic anhydride

: 52691-62-0,17364-21-5
1-palmityl-sn-glycero-3-phosphocholine

: 88587-94-4
L-1-hexadecyl-2-palmitoyl-phosphatidylcholine

Guidance literature:: With dmap; In chloroform; for 24h;
DOI:10.1021/jo00280a035

Reference yield:

: 36653-82-4,124-29-8
1-Hexadecanol

: 88587-94-4
L-1-hexadecyl-2-palmitoyl-phosphatidylcholine

Guidance literature:: Multi-step reaction with 4 steps

1.1: NaH / tetrahydrofuran / 1 h / 80 °C

1.2: tetrahydrofuran; dimethylformamide / 80 °C

2.1: 2.39 g / pyridine / petroleum ether / 16 h / 80 °C

3.1: H₂ / Pd/C / ethyl acetate / 1.5 h

4.1: POCl₃; Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

4.2: 159 mg / pyridine / CH₂Cl₂ / 16 h / 20 °C

With pyridine; hydrogen; sodium hydride; triethylamine; trichlorophosphate; palladium on activated charcoal; In tetrahydrofuran; dichloromethane; ethyl acetate; Petroleum ether;
DOI:10.1021/jm031029r

Reference yield:

: 88988-71-0
1-O-Hexadecyl-2-O-hydroxy-3-O-benzyl-sn-glycerol

: 88587-94-4
L-1-hexadecyl-2-palmitoyl-phosphatidylcholine

Guidance literature:: Multi-step reaction with 3 steps

1.1: 2.39 g / pyridine / petroleum ether / 16 h / 80 °C

2.1: H₂ / Pd/C / ethyl acetate / 1.5 h

3.1: POCl₃; Et₃N / CH₂Cl₂ / 0.5 h / 20 °C

3.2: 159 mg / pyridine / CH₂Cl₂ / 16 h / 20 °C

With pyridine; hydrogen; triethylamine; trichlorophosphate; palladium on activated charcoal; In dichloromethane; ethyl acetate; Petroleum ether;
DOI:10.1021/jm031029r