4-Fluoro-2-nitrobenzenethiol, 4-Fluoro-2-nitrophenyl mercaptan

Base Information

• Chemical Name: 4-Fluoro-2-nitrobenzenethiol, 4-Fluoro-2-nitrophenyl mercaptan
• CAS No.: 654063-68-0
• Molecular Formula: C6H4FNO2S
• Molecular Weight: 173.168
• Hs Code.: 2930909899
• Mol file: 654063-68-0.mol

Synonyms:4-FLUORO-2-NITROTHIOPHENOL;

Chemical Property of 4-Fluoro-2-nitrobenzenethiol, 4-Fluoro-2-nitrophenyl mercaptan

Chemical Property:

• PSA: 84.62000
• LogP: 2.54580

Purity/Quality:

98.5% ^*data from raw suppliers

4-Fluoro-2-nitrobenzenethiol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Fluoro-2-nitrobenzenethiol, 4-Fluoro-2-nitrophenyl mercaptan

There total 1 articles about 4-Fluoro-2-nitrobenzenethiol, 4-Fluoro-2-nitrophenyl mercaptan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitro-4-fluoroaniline (364-78-3) → 4-fluoro-2-nitrobenzenethiol (654063-68-0)

Guidance literature:

2-nitro-4-fluoroaniline; With sulfuric acid; sodium nitrite; In water; at 5 ℃; for 0.666667h;

With copper(I) thiocyanate; potassium thioacyanate; In water; at 5 ℃;

With Sodium sulfide; In ethanol; water; for 1h; pH=5; Heating / reflux; Acidic conditions;

Reference yield: 19.0%

4-fluoro-2-nitrobenzenethiol (654063-68-0) + malononitrile (109-77-3) → 2-(5-fluorobenzo[d]thiazol-2-yl)acetonitrile (157764-05-1)

Guidance literature:

4-fluoro-2-nitrobenzenethiol; With tin(ll) chloride; In ethanol; Heating / reflux;

malononitrile; In ethanol; for 5h; Heating / reflux;

upstream raw materials:

2-nitro-4-fluoroaniline

Downstream raw materials:

2-(5-fluorobenzo[d]thiazol-2-yl)acetonitrile