2H-Pyran-2-one, 3,4-diphenyl-6-(2-thienyl)-

Base Information

Chemical Name:2H-Pyran-2-one, 3,4-diphenyl-6-(2-thienyl)-
CAS No.:65439-00-1
Molecular Formula:C21H14O2S
Molecular Weight:330.407
Hs Code.:
DSSTox Substance ID:DTXSID80408661
Nikkaji Number:J1.595.394B
Wikidata:Q82214207

Synonyms:65439-00-1;3,4-diphenyl-6-thiophen-2-ylpyran-2-one;2H-Pyran-2-one, 3,4-diphenyl-6-(2-thienyl)-;3,4-Diphenyl-6-(2-thienyl)-2H-pyran-2-one;DTXSID80408661;AKOS001633202

Suppliers and Price of 2H-Pyran-2-one, 3,4-diphenyl-6-(2-thienyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2H-Pyran-2-one, 3,4-diphenyl-6-(2-thienyl)-

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:330.07145086
Heavy Atom Count:24
Complexity:536

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C(=O)OC(=C2)C3=CC=CS3)C4=CC=CC=C4

Technology Process of 2H-Pyran-2-one, 3,4-diphenyl-6-(2-thienyl)-

There total 3 articles about 2H-Pyran-2-one, 3,4-diphenyl-6-(2-thienyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 2-(dimethyl(oxo)-λ⁶-sulfaneylidene)-1-(thiophen-2-yl)ethan-1-one

: 886-38-4
diphenylcyclopropenone

: 65439-00-1
3,4-diphenyl-6-(thiophen-2-yl)-2H-pyran-2-one

Guidance literature:: With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate; In acetonitrile; at 100 ℃; for 24h; Inert atmosphere;
DOI:10.1021/acs.joc.9b02253

Reference yield: 44.0%

: 886-38-4
diphenylcyclopropenone

: 2-(dimethyl-λ⁴-sulfanylidene)-1-thiophen-2-yl-ethanone

: 65439-00-1
3,4-diphenyl-6-(thiophen-2-yl)-2H-pyran-2-one

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 3h;
DOI:10.1246/bcsj.74.1567

Reference yield:

: 102-04-5
1,3-Diphenylpropanone

: 65439-00-1
3,4-diphenyl-6-(thiophen-2-yl)-2H-pyran-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid; bromine / 3 h

1.2: 1 h / 20 °C

2.1: dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; sodium acetate / acetonitrile / 24 h / 100 °C / Inert atmosphere

With dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; bromine; sodium acetate; acetic acid; In acetonitrile;
DOI:10.1021/acs.joc.9b02253