1-Butanone, 4-iodo-1-phenyl

Base Information

• Chemical Name: 1-Butanone, 4-iodo-1-phenyl
• CAS No.: 65488-05-3
• Molecular Formula: C10H11IO
• Molecular Weight: 274.101
• Mol file: 65488-05-3.mol

Synonyms:4-iodo-1-phenyl-1-butanone;1-Benzoyl-3-iodopropane;4-iodobutyl phenyl ketone;4-iodo-1-phenylbutan-1-one;4-iodo-4-phenylbutan-1-one;γ-iodobutyrophenone;

Chemical Property of 1-Butanone, 4-iodo-1-phenyl

Chemical Property:

• Boiling Point: 313.8±25.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.586±0.06 g/cm3(Predicted)
• LogP: 3.08450

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Butanone, 4-iodo-1-phenyl

There total 8 articles about 1-Butanone, 4-iodo-1-phenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

→ 4-iodobutyrophenone (65488-05-3)

Guidance literature:

Reference yield: 89.0%

cyclopropyl phenyl ketone (3481-02-5) → 4-iodobutyrophenone (65488-05-3)

Guidance literature:

With diphosphorus tetraiodide; In acetone; at 20 ℃; for 2h;

DOI:10.1039/c39830000229

Reference yield: 88.0%

4-chloro-1-phenylbutan-1-one (939-52-6) → 4-iodobutyrophenone (65488-05-3)

Guidance literature:

With sodium iodide; In acetone; for 10h; Heating;

DOI:10.1021/ja0389366

upstream raw materials:

cyclopropyl phenyl ketone

4-bromo-1-phenyl-1-butanone

4-chloro-1-phenylbutan-1-one

benzene

Downstream raw materials:

1,8-Diphenyl-octane-1,5-dione

4-Phenylbutyric acid

propiophenone

4-chloro-1-phenylbutan-1-one

Refernces

• 1、 Huang, Feng-Qing,Xie, Jian,Sun, Jian-Guo,Wang, Yue-Wei,Dong, Xin,Qi, Lian-Wen,Zhang, Bo. "Regioselective Synthesis of Carbonyl-Containing Alkyl Chlorides via Silver-Catalyzed Ring-Opening Chlorination of Cycloalkanols". supporting information. p. 684 - 687. Retrieved 2016/03/01.
• 2、 Park, Ju-Young,Kim, Seung-Woo,Lee, Ja-Kyeong,Im, Weon Bin,Jin, Byung Kwan,Yoon, Sung-Hwa. "Simplified heterocyclic analogues of fluoxetine inhibit inducible nitric oxide production in lipopolysaccharide-induced BV2 cells". experimental part. p. 538 - 544. Retrieved 2012/02/15.