1,3-Dihydronaphtho[2,3-c]furan-1-ol

Base Information

Chemical Name:1,3-Dihydronaphtho[2,3-c]furan-1-ol
CAS No.:65539-69-7
Molecular Formula:C12H10O2
Molecular Weight:186.21
Hs Code.:
NSC Number:95814
DSSTox Substance ID:DTXSID00294321

Synonyms:65539-69-7;1,3-dihydronaphtho[2,3-c]furan-1-ol;NSC95814;DTXSID00294321;NSC-95814

Suppliers and Price of 1,3-Dihydronaphtho[2,3-c]furan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1,3-Dihydronaphtho[2,3-c]furan-1-ol

Chemical Property:

Vapor Pressure:5.59E-07mmHg at 25°C
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:186.068079557
Heavy Atom Count:14
Complexity:216

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C2=CC3=CC=CC=C3C=C2C(O1)O

Technology Process of 1,3-Dihydronaphtho[2,3-c]furan-1-ol

There total 3 articles about 1,3-Dihydronaphtho[2,3-c]furan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 939-15-1
2-bromo-3-methylnaphthalene

: 65539-69-7
3-(hydroxymethyl)-2-naphthaldehyde (1,3-dihydro-1-hydroxynaphtho<2,3-c>furan)

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / N-bromosuccinimide (NBS), benzoyl peroxide / CCl₄ / 3 h / Heating

2: 83 percent / aq. CaCO₃ / dioxane / 10 h / Heating

3: 1.) n-BuLi / 1.) diethyl ether, hexane, 0 deg C, 30 min, 2.) diethyl ether, hexane, 10 h

With N-Bromosuccinimide; n-butyllithium; Perbenzoic acid; calcium carbonate; In 1,4-dioxane; tetrachloromethane;
DOI:10.1021/jo00370a004

Reference yield:

: 38399-20-1
2-bromo-3-(bromomethyl)naphthalene

: 65539-69-7
3-(hydroxymethyl)-2-naphthaldehyde (1,3-dihydro-1-hydroxynaphtho<2,3-c>furan)

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / aq. CaCO₃ / dioxane / 10 h / Heating

2: 1.) n-BuLi / 1.) diethyl ether, hexane, 0 deg C, 30 min, 2.) diethyl ether, hexane, 10 h

With n-butyllithium; calcium carbonate; In 1,4-dioxane;
DOI:10.1021/jo00370a004

Reference yield:

: 38399-19-8
2-bromo-3-(hydroxymethyl)naphthalene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 65539-69-7
3-(hydroxymethyl)-2-naphthaldehyde (1,3-dihydro-1-hydroxynaphtho<2,3-c>furan)

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction; 1.) diethyl ether, hexane, 0 deg C, 30 min, 2.) diethyl ether, hexane, 10 h;
DOI:10.1021/jo00370a004