5-(1H-pyrazol-3-yl)thiophene-2-carboxylic acid

Base Information

Chemical Name:5-(1H-pyrazol-3-yl)thiophene-2-carboxylic acid
CAS No.:656226-63-0
Molecular Formula:C₈H₆N₂O₂S
Molecular Weight:194.214
Hs Code.:2934999090
European Community (EC) Number:877-983-5
DSSTox Substance ID:DTXSID90590743
Wikidata:Q82484385
Mol file:656226-63-0.mol

Synonyms:656226-63-0;5-(1H-pyrazol-3-yl)thiophene-2-carboxylic acid;5-(1H-Pyrazol-3-yl)-2-thiophenecarboxylic acid;5-(1H-pyrazol-5-yl)thiophene-2-carboxylic acid;MFCD08361642;SCHEMBL5903720;DTXSID90590743;STL415383;AKOS005168993;AS-47442;DB-295599;5-(1H-pyrazol-3-yl)thiophene-2-carboxylicacid;EN300-103394;F13752;Z1198177197

Suppliers and Price of 5-(1H-pyrazol-3-yl)thiophene-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(1H-pyrazol-3-yl)thiophene-2-carboxylicAcid
100mg
$ 285.00

TRC
5-(1H-pyrazol-3-yl)thiophene-2-carboxylicAcid
50mg
$ 175.00

Crysdot
5-(1H-Pyrazol-3-yl)thiophene-2-carboxylicacid 97%
1g
$ 474.00

American Custom Chemicals Corporation
5-(1H-PYRAZOL-3-YL)THIOPHENE-2-CARBOXYLIC ACID 95.00%
5MG
$ 498.65

AK Scientific
5-(1H-Pyrazol-3-yl)thiophene-2-carboxylicacid
10g
$ 1814.00

Total 3 raw suppliers

Chemical Property of 5-(1H-pyrazol-3-yl)thiophene-2-carboxylic acid

Chemical Property:

Vapor Pressure:3.38E-11mmHg at 25°C
Boiling Point:509.4oC at 760 mmHg
Flash Point:261.8oC
PSA：94.22000
Density:1.514g/cm3
LogP:1.83640
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:194.01499861
Heavy Atom Count:13
Complexity:212

Purity/Quality:

99% ^*data from raw suppliers

5-(1H-pyrazol-3-yl)thiophene-2-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(SC(=C1)C(=O)O)C2=CC=NN2

Technology Process of 5-(1H-pyrazol-3-yl)thiophene-2-carboxylic acid

There total 3 articles about 5-(1H-pyrazol-3-yl)thiophene-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 474707-58-9
5-(1H-pyrazol-3-yl)-thiophene-2-carbonitrile

: 656226-63-0
5-(1H-pyrazol-3-yl)-thiophene-2-carboxylic acid

Guidance literature:: With sodium hydroxide; water; for 2h; Heating / reflux;

Reference yield: 97.0%

: 656226-63-0
5-(1H-pyrazol-3-yl)-thiophene-2-carboxylic acid

Guidance literature:

Reference yield:

: 5-((E)-3-Dimethylamino-acryloyl)-thiophene-2-carbonitrile

: 656226-63-0
5-(1H-pyrazol-3-yl)-thiophene-2-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / hydrazine hydrate / ethanol / 16 h / Heating

2: aq. NaOH / 2 h / Heating

With sodium hydroxide; hydrazine hydrate; In ethanol;
DOI:10.1016/j.bmcl.2006.10.048