Juvabiol

Base Information

Chemical Name:Juvabiol
CAS No.:60134-56-7
Molecular Formula:C16H28O3
Molecular Weight:268.39
Hs Code.:
DSSTox Substance ID:DTXSID601338492
Nikkaji Number:J18.283D
Wikidata:Q104375746
Mol file:60134-56-7.mol

Synonyms:Juvabiol;60134-56-7;DTXSID601338492

Suppliers and Price of Juvabiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Juvabiol

Chemical Property:

PSA：46.53000
LogP:3.31910
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:268.20384475
Heavy Atom Count:19
Complexity:320

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(CC(C)C1CCC(=CC1)C(=O)OC)O
Isomeric SMILES:C[C@H](C[C@H](CC(C)C)O)[C@@H]1CCC(=CC1)C(=O)OC

Technology Process of Juvabiol

There total 26 articles about Juvabiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 80320-99-6
(R)-4-[(1R,3S)-3-(tert-Butyl-diphenyl-silanyloxy)-1,5-dimethyl-hexyl]-cyclohex-1-enecarboxylic acid methyl ester

: 60134-56-7
(+)-juvabiol

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 7h; Heating;
DOI:10.1021/jo00339a054

Reference yield: 48.0%

: 145353-92-0
methyl (1'R,4R)-4-(2'-formyl-1'-methylethyl)cyclohex-1-ene-1-carboxylate

: 926-62-5
isobutylmagnesium bromide

: 58493-52-0,60134-56-7,60497-70-3,64314-14-3,76549-67-2,80373-62-2
methyl (4R,1'R,3'RS)-(+)-4-(1',5'-dimethyl-3'-hydroxyhexyl)-1-cyclohexenecarboxylate

Guidance literature:: In tetrahydrofuran; at -45 ℃; for 3h;

Reference yield:

: tert-Butyl-[(1S,3R)-1-isobutyl-3-((R)-6-methyl-7-oxa-bicyclo[4.1.0]hept-3-yl)-butoxy]-diphenyl-silane

: 60134-56-7
(+)-juvabiol

Guidance literature:: Multi-step reaction with 6 steps

1: 92 percent / diethylaluminum 2,2,6,6-tetramethylpiperidide / benzene / 3 h / 0 °C

2: 30 percent / lithium diethylamide / diethyl ether

3: 65 percent / PBr₃ / tetrahydrofuran / 0 °C

4: 88 percent / 2-nitropropane, KOH / H₂O; tetrahydrofuran; propan-2-ol / 1 h / 40 - 50 °C

5: 87 percent / manganese dioxide / acetic acid / 12 h / 22 °C

6: 88 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 7 h / Heating

With manganese(IV) oxide; potassium hydroxide; diethyl(2,2,6,6-tetramethylpiperidino)aluminium; 2-nitropropane; lithium diethylamide; tetrabutyl ammonium fluoride; phosphorus tribromide; In tetrahydrofuran; diethyl ether; water; acetic acid; isopropyl alcohol; benzene;
DOI:10.1021/jo00339a054