2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE

Base Information

• Chemical Name: 2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE
• CAS No.: 5690-46-0
• Molecular Formula: C12H8 N2 O2
• Molecular Weight: 212.208
• Hs Code.: 2933990090
• Mol file: 5690-46-0.mol

Synonyms:Naphthalimide,N-amino- (6CI,8CI); N-Amino-1,8-naphthalimide; N-Aminonaphthalimide; NSC615807; NSC 80271

Chemical Property of 2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE

Chemical Property:

• Vapor Pressure: 9.44E-09mmHg at 25°C
• Melting Point: 265 °C
• Boiling Point: 463°Cat760mmHg
• Flash Point: 233.8°C
• PSA: 65.09000
• Density: 1.47g/cm³
• LogP: 1.24770
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

98%min ^*data from raw suppliers

2-Amino-benzo[de]isoquinoline-1,3-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2-Amino-benzo[de]isoquinoline-1,3-dione is an antiviral compound that exhibits antiherpetic activity against herpes simplex viruses HSV-1 and HSV-2.

Technology Process of 2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE

There total 52 articles about 2-AMINO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-1,3-DIONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

N-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-1-naphthamide → 2-amino-1H-benzo[de]isoquinoline-1,3(2H)-dione (5690-46-0) + 1-naphthohydrazide (43038-45-5)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Reflux;

DOI:10.1002/chem.202102593

Reference yield: 94.0%

N-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)-4-methoxybenzamide → 2-amino-1H-benzo[de]isoquinoline-1,3(2H)-dione (5690-46-0) + 4-methoxybenzoic acid hydrazide (3290-99-1)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Reflux;

DOI:10.1002/chem.202102593

Reference yield: 93.0%

N-(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)propanamide (19162-43-7) → 2-amino-1H-benzo[de]isoquinoline-1,3(2H)-dione (5690-46-0) + d'hydrazide de l'acide propionique (5818-15-5)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Reflux;

DOI:10.1002/chem.202102593

Downstream raw materials:

2-(3-phenyl-propylidenamino)-benz[de]isoquinoline-1,3-dione

10-phenyl-benzo[de][1,2,4]triazolo[5,1-a]isoquinolin-7-one

2-(3-nitro-benzylidenamino)-benz[de]isoquinoline-1,3-dione

2-(4-nitro-benzylidenamino)-benz[de]isoquinoline-1,3-dione