Benzeneacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-

Base Information

Chemical Name:Benzeneacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-
CAS No.:65808-73-3
Molecular Formula:C24H20Cl2N2O3
Molecular Weight:455.3332
Hs Code.:2924299090
DSSTox Substance ID:DTXSID80216001
Wikidata:Q83092126
ChEMBL ID:CHEMBL90870
Mol file:65808-73-3.mol

Synonyms:65808-73-3;BRN 5165006;Benzeneacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-;N-(2-((4-Chloro-2-(2-chlorobenzoyl)phenyl)methylamin0)-2-oxoethyl)benzeneacetamide;CHEMBL90870;C24H20Cl2N2O3;DTXSID80216001;C24-H20-Cl2-N2-O3;N-[4-CHLORO-2-(2-CHLOROBENZOYL)PHENYL]-N-METHYL-2-[(2-PHENYLACETYL)AMI NO]ACETAMIDE;LS-28489

Suppliers and Price of Benzeneacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzeneacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-

Chemical Property:

Vapor Pressure:1.36E-19mmHg at 25°C
Boiling Point:702.7°Cat760mmHg
PKA:14.56±0.46(Predicted)
Flash Point:378.8°C
PSA：69.97000
Density:1.328g/cm³
LogP:5.38640
XLogP3:4.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:7
Exact Mass:454.0850979
Heavy Atom Count:31
Complexity:638

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C1=C(C=C(C=C1)Cl)C(=O)C2=CC=CC=C2Cl)C(=O)CNC(=O)CC3=CC=CC=C3

Technology Process of Benzeneacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)-

There total 2 articles about Benzeneacetamide, N-(2-((4-chloro-2-(2-chlorobenzoyl)phenyl)methylamino)-2-oxoethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.3%

: 59180-41-5
4-chloro-2-(o-chlorobenzoyl)-N-methyl-N^α-glycinanilide hydrobromide

: 65808-73-3
N-({[4-Chloro-2-(2-chloro-benzoyl)-phenyl]-methyl-carbamoyl}-methyl)-2-phenyl-acetamide

Guidance literature:: In N,N-dimethyl-formamide; for 3.5h; Ambient temperature;
DOI:10.1021/jm00133a006

Reference yield:

: 29176-39-4
4-chloro-2-(o-chlorobenzoyl)-N^α-(benzyloxycarbonyl)glycinanilide

: 65808-73-3
N-({[4-Chloro-2-(2-chloro-benzoyl)-phenyl]-methyl-carbamoyl}-methyl)-2-phenyl-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) DMF, oil, 2-5 deg C, 15 min, 2.) DMF, oil, 2-5 deg C, 2 h

2: 97 percent / 20percent HBr / acetic acid / 1 h / Ambient temperature

3: 85.3 percent / dimethylformamide / 3.5 h / Ambient temperature

With hydrogen bromide; sodium hydride; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1021/jm00133a006