Butanoic acid, 4-oxo-4-((3-(2-quinolinylmethoxy)phenyl)amino)-, methyl ester

Base Information

Chemical Name:Butanoic acid, 4-oxo-4-((3-(2-quinolinylmethoxy)phenyl)amino)-, methyl ester
CAS No.:102649-84-3
Molecular Formula:C21H20 N2 O4
Molecular Weight:364.401
Hs Code.:
ChEMBL ID:CHEMBL288778
DSSTox Substance ID:DTXSID30145438
Wikidata:Q83009991
Mol file:102649-84-3.mol

Synonyms:Succinamic acid, N-(m-(2-quinolinylmethoxy)phenyl)-, methyl ester;Butanoic acid, 4-oxo-4-((3-(2-quinolinylmethoxy)phenyl)amino)-, methyl ester;CHEMBL288778;102649-84-3;N-(m-(2-Quinolinylmethoxy)phenyl)succinamic acid methyl ester;SCHEMBL8180018;DTXSID30145438;BDBM50022196;N-[3-(Quinolin-2-ylmethoxy)-phenyl]-succinamic acid methyl ester

Suppliers and Price of Butanoic acid, 4-oxo-4-((3-(2-quinolinylmethoxy)phenyl)amino)-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Butanoic acid, 4-oxo-4-((3-(2-quinolinylmethoxy)phenyl)amino)-, methyl ester

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:364.14230712
Heavy Atom Count:27
Complexity:499

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CCC(=O)NC1=CC(=CC=C1)OCC2=NC3=CC=CC=C3C=C2

Technology Process of Butanoic acid, 4-oxo-4-((3-(2-quinolinylmethoxy)phenyl)amino)-, methyl ester

There total 4 articles about Butanoic acid, 4-oxo-4-((3-(2-quinolinylmethoxy)phenyl)amino)-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 105326-65-6
3-[(2-quinolinyl)methoxy]benzenamine

: 1490-25-1
succinic acid monomethylester chloride

: 102649-84-3
4-{[3-(2-quinolinylmethoxy)phenyl]amino}-4-oxobutanoic acid methyl ester

Guidance literature:: With triethylamine; In tetrahydrofuran; for 1h; Ambient temperature;
DOI:10.1021/jm00158a019

Reference yield:

: 4377-41-7
2-Chloromethylquinoline

: 102649-84-3
4-{[3-(2-quinolinylmethoxy)phenyl]amino}-4-oxobutanoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: cesium carbonate, sodium carbonate, potassium iodide / acetone / 72 h / Heating

2: hydrochloric acid, iron / ethanol / Ambient temperature

3: 69 percent / triethylamine / tetrahydrofuran / 1 h / Ambient temperature

With hydrogenchloride; iron; sodium carbonate; caesium carbonate; triethylamine; potassium iodide; In tetrahydrofuran; ethanol; acetone;
DOI:10.1021/jm00158a019

Reference yield:

: 554-84-7
meta-nitrophenol

: 102649-84-3
4-{[3-(2-quinolinylmethoxy)phenyl]amino}-4-oxobutanoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: cesium carbonate, sodium carbonate, potassium iodide / acetone / 72 h / Heating

2: hydrochloric acid, iron / ethanol / Ambient temperature

3: 69 percent / triethylamine / tetrahydrofuran / 1 h / Ambient temperature

With hydrogenchloride; iron; sodium carbonate; caesium carbonate; triethylamine; potassium iodide; In tetrahydrofuran; ethanol; acetone;
DOI:10.1021/jm00158a019