5-CHLORONAPHTHALENE-1-SULFONYL CHLORIDE

Base Information

• Chemical Name: 5-CHLORONAPHTHALENE-1-SULFONYL CHLORIDE
• CAS No.: 6291-07-2
• Molecular Formula: C10H6Cl2O2S
• Molecular Weight: 261.128
• Hs Code.: 2904909090
• Mol file: 6291-07-2.mol

Synonyms:5-Chloro-1-naphthalenesulfonylchloride;NSC 4618;5-Chloronaphthalene-1-sulfonyl Chloride;5-Chloronaphthalene-1-sulphonyl chloride;

Chemical Property of 5-CHLORONAPHTHALENE-1-SULFONYL CHLORIDE

Chemical Property:

• Appearance/Colour: Yellow Crystalline Solid
• Vapor Pressure: 1.68E-05mmHg at 25°C
• Melting Point: 94-95 °C
• Refractive Index: 1.649
• Boiling Point: 375.4 °C at 760 mmHg
• Flash Point: 180.9 °C
• PSA: 42.52000
• Density: 1.516 g/cm³
• LogP: 4.50150
• Storage Temp.: -20°C Freezer
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly)

Purity/Quality:

99%min ^*data from raw suppliers

5-Chloronaphthalene-1-sulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 5-Chloronaphthalene-1-sulfonyl Chloride (cas# 6291-07-2) is a compound useful in organic synthesis.

Technology Process of 5-CHLORONAPHTHALENE-1-SULFONYL CHLORIDE

There total 4 articles about 5-CHLORONAPHTHALENE-1-SULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.5%

5-chloronaphthalene-1-sulfonic acid (89108-43-0) → 5-chloro-1-naphthalenesulfonyl chloride (6291-07-2)

Guidance literature:

With phosphorus pentachloride; at 20 ℃;

DOI:10.1021/jm060414o

Reference yield:

1-aminonaphthalene-5-sulfonic acid (84-89-9) → 5-chloro-1-naphthalenesulfonyl chloride (6291-07-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) conc. HCl, 10percent aq. NaNO₂, 2.) 2 M CuCl, conc. HCl / 1.) 8percent aq. NaOH, 0-5 deg C, 6 h, 2.) room temp., overnight

2: PCl₅

With hydrogenchloride; phosphorus pentachloride; copper(l) chloride; sodium nitrite;

DOI:10.1002/ardp.19843170715

Reference yield:

→ 5-chloro-1-naphthalenesulfonyl chloride (6291-07-2)

Guidance literature:

With phosphorus pentachloride;

upstream raw materials:

5-chloronaphthalene-1-sulfonic acid

1-aminonaphthalene-5-sulfonic acid

Downstream raw materials:

1,5-dichloronaphthalene

Refernces

• 1、 -. "Substituted Disulfonamide Compounds". Page/Page column 48. . Retrieved 2010/06/22.