6,10-Dihydroxy Buspirone

Base Information

• Chemical Name: 6,10-Dihydroxy Buspirone
• CAS No.: 658701-59-8
• Molecular Formula: C₂₁H₃₁N₅O₄
• Molecular Weight: 417.508
• Mol file: 658701-59-8.mol

Synonyms:6,10-dihydroxy-8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione;

Chemical Property of 6,10-Dihydroxy Buspirone

Chemical Property:

• Melting Point: 190-194°C
• PSA: 110.10000
• LogP: -0.02940
• Storage Temp.: -20°C Freezer
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

6,10-Dihydroxy buspirone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 6,10-Dihydroxy Buspirone is an Impurity formed during the preparation of Buspirone metabolites. Also, it is derived from Buspirone (B689855), which is a non-benzodiazepine anxiolytic; 5-hydroxytryptamine (5-HT1) receptor agonist. Impurity formed during the preparation of Buspirone metabolites.

Technology Process of 6,10-Dihydroxy Buspirone

There total 1 articles about 6,10-Dihydroxy Buspirone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

BUSPIRONE (36505-84-7) → 6'-Hydroxybuspirone (125481-61-0) + 6,10-dihydroxybuspirone (658701-59-8)

Guidance literature:

With sodium hexamethyldisilazane; triethyl phosphite; In tetrahydrofuran; at -60 - 20 ℃; Large scale;

DOI:10.1021/op049918r

upstream raw materials:

BUSPIRONE

Refernces