holothurin B

Base Information

• Chemical Name: holothurin B
• CAS No.: 11052-32-7
• Molecular Formula: C41H64 O17 S . Na
• Molecular Weight: 882.997
• Mol file: 11052-32-7.mol

Synonyms:Lanost-9(11)-en-18-oicacid, 3-[[2-O-(6-deoxy-b-D-glucopyranosyl)-4-O-sulfo-b-D-xylopyranosyl]oxy]-22,25-epoxy-12,17,20-trihydroxy-, g-lactone, monosodium salt, (3b,12a,22S)- (9CI); Holothurin B

Chemical Property of holothurin B

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 268.64000
• Density: g/cm³
• LogP: 2.17180

Purity/Quality:

98%,99%, ^*data from raw suppliers

HOLOTHURIN B 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of holothurin B

There total 2 articles about holothurin B which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

holothurin A (38-26-6) → C35H53O13S(1-)*Na(1+) (67332-06-3,79389-96-1) + holothurin B (11052-32-7)

Guidance literature:

With naringinase; In water; at 34 ℃; for 96h; Product distribution; structure investigation;

DOI:10.1248/cpb.29.1951

Reference yield:

holothurin A (38-26-6) → C35H53O13S(1-)*Na(1+) (67332-06-3,79389-96-1) + holothurin B (11052-32-7) + C35H54O10 (67304-15-8,79389-51-8)

Guidance literature:

With AcOH buffer; glucosidase mixture; at 40 ℃; for 336h; Product distribution; structure investigation;

DOI:10.1248/cpb.29.1951

Reference yield:

holothurin B (11052-32-7) → Acetic acid (3S,3aR,5aS,9S,11aS)-3-((S)-5,5-dimethyl-tetrahydro-furan-2-yl)-3a-hydroxy-3,5a,8,8,11a-pentamethyl-1-oxo-3a,4,5,5a,7,7a,8,9,10,11,11a,13-dodecahydro-3H-2-oxa-pentaleno[1,6a-a]phenanthren-9-yl ester (6584-69-6,56143-26-1,79389-50-7)

Guidance literature:

Multi-step reaction with 2 steps

1: HCl / 3 h / 100 °C

2: pyridine / 18 h / Ambient temperature

With hydrogenchloride; In pyridine;

DOI:10.1248/cpb.29.1942

upstream raw materials:

holothurin A

Downstream raw materials:

Acetic acid (3S,3aR,5aS,9S,11aS)-3-((S)-5,5-dimethyl-tetrahydro-furan-2-yl)-3a-hydroxy-3,5a,8,8,11a-pentamethyl-1-oxo-3a,4,5,5a,7,7a,8,9,10,11,11a,13-dodecahydro-3H-2-oxa-pentaleno[1,6a-a]phenanthren-9-yl ester