5-Iodo-2-(methylamino)benzamide

Base Information

• Chemical Name: 5-Iodo-2-(methylamino)benzamide
• CAS No.: 660436-78-2
• Molecular Formula: C8H9IN2O
• Molecular Weight: 276.077
• Mol file: 660436-78-2.mol

Synonyms:5-iodo-2-methylamino-benzamide;Benzamide,5-iodo-2-(methylamino);

Chemical Property of 5-Iodo-2-(methylamino)benzamide

Chemical Property:

• Boiling Point: 342.7±37.0 °C(Predicted)
• PKA: 15.26±0.50(Predicted)
• PSA: 55.12000
• Density: 1.844±0.06 g/cm3(Predicted)
• LogP: 2.20510

Purity/Quality:

98%min ^*data from raw suppliers

5-Iodo-2-(methylamino)benzamide 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-Iodo-2-(methylamino)benzamide

There total 1 articles about 5-Iodo-2-(methylamino)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

5-Iodo-2-methylamino-benzoic acid (151979-21-4) → 5-iodo-2-methylamino-benzamide (660436-78-2)

Guidance literature:

With ammonia; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In tetrahydrofuran; 1,4-dioxane; at 0 - 20 ℃; for 16h;

Reference yield: 92.0%

5-iodo-2-methylamino-benzamide (660436-78-2) → (2-aminomethyl-4-iodo-phenyl)-methyl-amine (660436-79-3)

Guidance literature:

5-iodo-2-methylamino-benzamide; With borane-THF; In tetrahydrofuran; for 4h; Heating / reflux;

With sodium hydroxide; water;

upstream raw materials:

5-Iodo-2-methylamino-benzoic acid

Downstream raw materials:

(2-aminomethyl-4-iodo-phenyl)-methyl-amine

Refernces