6-[(Z)-prop-1-enyl]-1,3-benzodioxole-5-carbaldehyde

Base Information

Chemical Name:6-[(Z)-prop-1-enyl]-1,3-benzodioxole-5-carbaldehyde
CAS No.:6625-66-7
Molecular Formula:C₁₁H₁₀O₃
Molecular Weight:190.199
Hs Code.:
NSC Number:15674
DSSTox Substance ID:DTXSID60417832
Wikidata:Q82228040

Synonyms:NSC15674;6625-66-7;DTXSID60417832;NSC-15674

Suppliers and Price of 6-[(Z)-prop-1-enyl]-1,3-benzodioxole-5-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 6-[(Z)-prop-1-enyl]-1,3-benzodioxole-5-carbaldehyde

Chemical Property:

Vapor Pressure:0.000166mmHg at 25°C
Boiling Point:330.5°Cat760mmHg
Flash Point:144.8°C
Density:1.241g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:190.062994177
Heavy Atom Count:14
Complexity:237

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC=CC1=CC2=C(C=C1C=O)OCO2
Isomeric SMILES:C/C=C\C1=CC2=C(C=C1C=O)OCO2

Technology Process of 6-[(Z)-prop-1-enyl]-1,3-benzodioxole-5-carbaldehyde

There total 4 articles about 6-[(Z)-prop-1-enyl]-1,3-benzodioxole-5-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: potassium trifluoro(prop-1-en-1-yl)borate

: 15930-53-7
6-bromo-3,4-methylenedioxybenzaldehyde

: 6625-66-7
(E)-6-(prop-1-en-1-yl)benzo[d][1,3]dioxole-5-carbaldehyde

Guidance literature:: With palladium diacetate; caesium carbonate; triphenylphosphine; In tetrahydrofuran; water; at 70 ℃; for 4h;
DOI:10.1002/anie.202001069

Reference yield:

: C₁₀H₉BrO₂

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 6625-66-7
(E)-6-(prop-1-en-1-yl)benzo[d][1,3]dioxole-5-carbaldehyde

Guidance literature:: C₁₀H₉BrO₂; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 ℃; for 5h;
DOI:10.1039/d1cc03568a

Reference yield:

: C₁₀H₉BrO₂

: 6625-66-7
(E)-6-(prop-1-en-1-yl)benzo[d][1,3]dioxole-5-carbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: dichloro bis(acetonitrile) palladium(II) / chloroform / 72 h / 50 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 °C

2.2: 5 h / -78 °C

With dichloro bis(acetonitrile) palladium(II); n-butyllithium; In tetrahydrofuran; hexane; chloroform;
DOI:10.1039/d1cc03568a