2'-deoxyxanthosine

Base Information

• Chemical Name: 2'-deoxyxanthosine
• CAS No.: 29049-22-7
• Molecular Formula: C10H12 N4 O5
• Molecular Weight: 268.229
• Mol file: 29049-22-7.mol

Synonyms:2'-Deoxyxanthosine;9-(2'-Deoxy-b-D-ribosyl)xanthine;Xanthine 9-(b-D-deoxyriboside)

Chemical Property of 2'-deoxyxanthosine

Chemical Property:

• Melting Point: >230°C (dec.)
• Boiling Point: 775.6°Cat760mmHg
• PKA: 7.33±0.70(Predicted)
• Flash Point: 422.9°C
• PSA: 133.23000
• Density: 2.08g/cm³
• LogP: -1.94640
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Water (Slightly, Sonicated)

Purity/Quality:

97% ^*data from raw suppliers

2''-Deoxyxanthosine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2'-deoxyxanthosine

There total 11 articles about 2'-deoxyxanthosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2'-deoxyisoinosine (67616-35-7) → 2'-deoxyxanthosine (29049-22-7,25843-96-3)

Guidance literature:

With xanthine oxidase; In water; for 10h; Ambient temperature; pH 7.4;

Reference yield: 56.0%

2'-Deoxyguanosine (961-07-9) → 2'-deoxyxanthosine (29049-22-7,25843-96-3)

Guidance literature:

With sodium nitroprusside; sodium hydroxide; at 70 ℃; for 4h;

DOI:10.1016/S0040-4039(00)99492-9

Reference yield: 40.0%

N1-hydroxy-2'-deoxyinosine (194287-64-4) → 2-deoxyinosine (890-38-0) + 2'-deoxyxanthosine (29049-22-7,25843-96-3) + 2'-deoxyoxanosine (88899-00-7)

Guidance literature:

In water; for 2h; Ambient temperature; Irradiation;

DOI:10.1016/S0040-4039(98)01605-0

upstream raw materials:

2'-Deoxyguanosine

2'-deoxyisoinosine

5-(benzyloxycarbonyl)amino-1-(2-deoxy-β-D-ribofuranosyl)imidazole-4-carboxamide

N₁-hydroxy-2'-deoxyinosine

Refernces

• 1、 Aoyama, Shuhei,Sano, Kayoko,Asahi, Chiharu,Machida, Masaki,Okamoto, Keinosuke,Negishi, Tomoe,Kimura, Sachiko,Suzuki, Toshinori,Hatano, Tsutomu,Arimoto-Kobayashi, Sakae. "Near ultraviolet radiation-mediated reaction between N-nitrosoproline and DNA: Isolation and identification of two new adducts, (R)- and (S)-8-(2-pyrrolidyl)-2′-deoxyguanosine". . p. 1 - 7. Retrieved 2014/01/23.
• 2、 Seela, Frank,Chen, Yaoming,Sauer, Markus. "Synthesis of 2',3'-didehydro-2',3'-dideoxyisoinosine and oxidation of fluorescent 2-hydroxypurine nucleosides by xanthine oxidase". . p. 39 - 52. Retrieved 2007/10/03.