Ethanol, 2,2'-[1,2-cyclohexanediylbis(oxy)]bis-, cis-

Base Information

• Chemical Name: Ethanol, 2,2'-[1,2-cyclohexanediylbis(oxy)]bis-, cis-
• CAS No.: 66513-49-3
• Molecular Formula: C10H20O4
• Molecular Weight: 204.266
• Mol file: 66513-49-3.mol

Synonyms:

Chemical Property of Ethanol, 2,2'-[1,2-cyclohexanediylbis(oxy)]bis-, cis-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethanol, 2,2'-[1,2-cyclohexanediylbis(oxy)]bis-, cis-

There total 10 articles about Ethanol, 2,2'-[1,2-cyclohexanediylbis(oxy)]bis-, cis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2,2'-(1,2-phenylenedioxy)diethanol (10234-40-9) → 2,2'-(((1R,2S)-cyclohexane-1,2-diyl)bis(oxy))bis(ethan-1-ol) (66513-49-3)

Guidance literature:

With hydrogen; rhodium on strontium titanate; In methanol; chloroform; for 12h; under 760 Torr; Ambient temperature;

Reference yield:

(1R,2S)-1,2-bis(2-((tetrahydro-2H-pyran-2-yl)oxy)ethoxy)cyclohexane → 2,2'-(((1R,2S)-cyclohexane-1,2-diyl)bis(oxy))bis(ethan-1-ol) (66513-49-3)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; methanol; for 1h; Reflux;

Reference yield:

trans-1,2-cyclohexandiol (1460-57-7) → 2-[(1R,2R)-2-(2-Hydroxy-ethoxy)-cyclohexyloxy]-ethanol (62583-84-0,62623-97-6,66513-48-2,66513-49-3,75503-88-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 50percent aq. sodium hydroxide / tetrabutylammonium hydrogen sulfate / 72 h / 65 °C

2: aq. HCl / methanol; CH₂Cl₂ / 2 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In methanol; dichloromethane;

DOI:10.1021/jo00265a026

upstream raw materials:

trans-1,2-cyclohexandiol

meso-diethyl 2,2'-[cyclohexane-1,2-diylbis(oxy)]diacetate

2,2'-(1,2-phenylenedioxy)diethanol

dicyclohexano-18-crown-6

Downstream raw materials:

(((1R,2S)-cyclohexane-1,2-diyl)bis(oxy))bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate)