Phosphonic acid, (1-amino-2-phenylethyl)-, (S)-

Base Information

• Chemical Name: Phosphonic acid, (1-amino-2-phenylethyl)-, (S)-
• CAS No.: 66609-42-5
• Molecular Formula: C8H12NO3P
• Molecular Weight: 201.162
• Hs Code.: 2931499090
• Mol file: 66609-42-5.mol

Synonyms:(S)-(1-Amino-2-phenylethyl)phosphonsaeure;(S)-1-amino-2-phenylethanephosphonic acid;(S)-(1-amino-2-phenylethyl)phosphonic acid;(+)-(1-amino-2-phenylethyl)phosphonic acid;(S)-PheP;((S)-1-Amino-2-phenyl-ethyl)-phosphonic acid;S-1-amino-2-phenylethylphosphonic acid;

Chemical Property of Phosphonic acid, (1-amino-2-phenylethyl)-, (S)-

Chemical Property:

• PSA: 93.36000
• LogP: 1.39190

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phosphonic acid, (1-amino-2-phenylethyl)-, (S)-

There total 34 articles about Phosphonic acid, (1-amino-2-phenylethyl)-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

S-diphenyl (1-(N-dibenzoyl-L-tartarylamino)-2-phenyl)ethylphosphonate → D-Phenylalanine phosphonate (66609-42-5)

Guidance literature:

With hydrogen bromide; acetic acid; In water; for 20h; Heating;

DOI:10.1021/jo000014n

Reference yield: 87.0%

[(S)-2-Phenyl-1-((R)-1-phenyl-ethylamino)-ethyl]-phosphinic acid → D-Phenylalanine phosphonate (66609-42-5)

Guidance literature:

With water; bromine; at 70 ℃; for 8h;

DOI:10.1016/0040-4039(95)00750-7

Reference yield: 86.0%

[(S)-1-((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ5-benzo[1,3,2]diazaphosphol-2-yl)-2-phenyl-ethyl]-[1,3]dithiolan-2-ylidene-amine (132075-98-0) → D-Phenylalanine phosphonate (66609-42-5)

Guidance literature:

With hydrogenchloride; dihydrogen peroxide;

DOI:10.1016/S0040-4039(00)97092-8

upstream raw materials:

(1-Amino-2-phenylethyl)phosphonsaeure-diethylester

(1-Amino-2-phenyl-ethyl)-phosphonic acid dimethyl ester

N-[1-((2S,4S,5R)-3,4-Dimethyl-2-oxo-5-phenyl-2λ⁵-[1,3,2]oxazaphospholidin-2-yl)-2-phenyl-ethyl]-benzamide

[(S)-1-((3aS,7aS)-1,3-Dimethyl-2-oxo-octahydro-2λ⁵-benzo[1,3,2]diazaphosphol-2-yl)-2-phenyl-ethyl]-[1,3]dithiolan-2-ylidene-amine

Downstream raw materials:

(S)-1--2-phenylethyl phosphonic acid

(S)-(1-Amino-2-phenylethyl)phosphonsaeure-diethylester

S-H-ethyl-(1-(N-t-butoxycarbonylamino)-2-phenyl)ethylphosphonate

S-ethyl, 2-(2'-imidazolyl)-4-ethenylphenyl (1-(N-tert-butoxycarbonylamino)-2-phenyl)ethylphosphonate