4,6-Dimethyl-1-(2-oxo-2-phenylethyl)pyrimidin-2(1H)-one

Base Information

Chemical Name:4,6-Dimethyl-1-(2-oxo-2-phenylethyl)pyrimidin-2(1H)-one
CAS No.:66653-09-6
Molecular Formula:C₁₄H₁₄N₂O₂
Molecular Weight:242.277
Hs Code.:
DSSTox Substance ID:DTXSID80504379
Wikidata:Q82358839

Synonyms:66653-09-6;DTXSID80504379;4,6-Dimethyl-1-(2-oxo-2-phenylethyl)pyrimidin-2(1H)-one;AKOS011293505

Suppliers and Price of 4,6-Dimethyl-1-(2-oxo-2-phenylethyl)pyrimidin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 4,6-Dimethyl-1-(2-oxo-2-phenylethyl)pyrimidin-2(1H)-one

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:242.105527694
Heavy Atom Count:18
Complexity:418

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=NC(=O)N1CC(=O)C2=CC=CC=C2)C

Technology Process of 4,6-Dimethyl-1-(2-oxo-2-phenylethyl)pyrimidin-2(1H)-one

There total 1 articles about 4,6-Dimethyl-1-(2-oxo-2-phenylethyl)pyrimidin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 66653-09-6
4,6-dimethyl-1-(2-oxo-2-phenyl-ethyl)-1H-pyrimidin-2-one

Guidance literature:: 2-Hydroxy-4,6-dimethylpyrimidin, Phenacylbromid (A., Δ);
DOI:10.1021/jo00412a029

Reference yield: 90.0%

: 66653-09-6
4,6-dimethyl-1-(2-oxo-2-phenyl-ethyl)-1H-pyrimidin-2-one

: 66653-06-3
1,2-dihydro-1-oxo-3-methyl-6-phenylpyrrolo<1,2-c>pyrimidine

Guidance literature:: With sodium methylate; for 0.0833333h; Heating; further reagents (hydrazine, phenylhydrazine, triethylamine, hydroxylamine, semicarbazide);
DOI:10.1007/BF00955787

Reference yield:

: 66653-09-6
4,6-dimethyl-1-(2-oxo-2-phenyl-ethyl)-1H-pyrimidin-2-one

: 1,2-dihydro-1-oxo-2,3-dimethyl-6-phenylpyrrolo<1,2-c>pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / 180 - 200 °C

2: 1.) CH₃ONa / 1) 1 h, 2) 30 min

With sodium methylate;
DOI:10.1007/BF00955787