Linagliptin iMpurity G

Base Information

• Chemical Name: Linagliptin iMpurity G
• CAS No.: 668270-11-9
• Molecular Formula: C25H28N8O2
• Molecular Weight: 472.54200
• Mol file: 668270-11-9.mol

Synonyms:1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-(3-(S)-amino-piperidin-1-yl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purine;

Chemical Property of Linagliptin iMpurity G

Chemical Property:

• Melting Point: >162°C (dec.)
• Boiling Point: 661.2±65.0 °C(Predicted)
• PKA: 10.01±0.20(Predicted)
• PSA: 116.86000
• Density: 1.39±0.1 g/cm3(Predicted)
• LogP: 1.91270
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

(S)-Linagliptin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (S)-Linagliptin is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.

Technology Process of Linagliptin iMpurity G

There total 1 articles about Linagliptin iMpurity G which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-[(4-methyl-quinazolin-2-yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-((S)-3-amino-piperidin-1-yl)xanthine (668270-11-9,668270-12-0)

Guidance literature:

Refernces