5-(2-Fluorophenyl)-1,2-oxazole-3-carboxylic acid

Base Information

Chemical Name:5-(2-Fluorophenyl)-1,2-oxazole-3-carboxylic acid
CAS No.:668970-73-8
Molecular Formula:C10H6FNO3
Molecular Weight:207.161
Hs Code.:2934999090
European Community (EC) Number:848-627-6
DSSTox Substance ID:DTXSID20588411
Wikidata:Q82481069
Mol file:668970-73-8.mol

Synonyms:668970-73-8;5-(2-fluorophenyl)isoxazole-3-carboxylic acid;5-(2-fluorophenyl)-1,2-oxazole-3-carboxylic acid;SCHEMBL70022;DTXSID20588411;QVWCQOSJFUMRFM-UHFFFAOYSA-N;MFCD07377266;AKOS000138289;AT15622;CCG-311884;MCULE-7635345651;NCGC00334642-01;5-(2-fluorophenyl)isoxazole-3-carboxylicacid;EN300-36658;5-(2-fluoro-phenyl)-isoxazole-3-carboxylic acid;AB01327279-02;F2135-0583;Z240119382

Suppliers and Price of 5-(2-Fluorophenyl)-1,2-oxazole-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(2-fluorophenyl)-1,2-oxazole-3-carboxylicAcid
50mg
$ 65.00

TRC
5-(2-fluorophenyl)-1,2-oxazole-3-carboxylicAcid
25mg
$ 45.00

TRC
5-(2-fluorophenyl)-1,2-oxazole-3-carboxylicAcid
250mg
$ 285.00

Atlantic Research Chemicals
5-(2-Fluorophenyl)isoxazole-3-carboxylicacid 95%
1gm:
$ 279.23

American Custom Chemicals Corporation
5-(2-FLUOROPHENYL)ISOXAZOLE-3-CARBOXYLIC ACID 95.00%
5G
$ 1590.46

American Custom Chemicals Corporation
5-(2-FLUOROPHENYL)ISOXAZOLE-3-CARBOXYLIC ACID 95.00%
2.5G
$ 1255.54

American Custom Chemicals Corporation
5-(2-FLUOROPHENYL)ISOXAZOLE-3-CARBOXYLIC ACID 95.00%
1G
$ 867.10

AK Scientific
5-(2-Fluorophenyl)-1,2-oxazole-3-carboxylicacid
5g
$ 1723.00

AK Scientific
5-(2-Fluorophenyl)-1,2-oxazole-3-carboxylicacid
250mg
$ 332.00

Total 8 raw suppliers

Chemical Property of 5-(2-Fluorophenyl)-1,2-oxazole-3-carboxylic acid

Chemical Property:

PSA：63.33000
LogP:2.17890
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:207.03317122
Heavy Atom Count:15
Complexity:249

Purity/Quality:

NLT 98% ^*data from raw suppliers

5-(2-fluorophenyl)-1,2-oxazole-3-carboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=CC(=NO2)C(=O)O)F

Technology Process of 5-(2-Fluorophenyl)-1,2-oxazole-3-carboxylic acid

There total 7 articles about 5-(2-Fluorophenyl)-1,2-oxazole-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 668970-74-9
methyl 5-(2-fluorophenyl)isoxazole-3-carboxylate

: 668970-73-8
5-(2-fluorophenyl)isoxazole-3-carboxylic acid

Guidance literature:: With lithium hydroxide; In methanol; water;

Reference yield:

: 1126636-56-3
ethyl 5-(2-fluorophenyl)isooxazole-3-carboxylate

: 668970-73-8
5-(2-fluorophenyl)isoxazole-3-carboxylic acid

Guidance literature:: With potassium hydroxide; In methanol; Reflux;
DOI:10.1002/cbdv.201800433

Reference yield:

: 741286-80-6
ethyl 4-(2-fluorophenyl)-2,4-dioxobutanoate

: 668970-73-8
5-(2-fluorophenyl)isoxazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride / ethanol / Reflux

2: potassium hydroxide / methanol / Reflux

With hydroxylamine hydrochloride; potassium hydroxide; In methanol; ethanol;
DOI:10.1002/cbdv.201800433