Cyclopentanone, 2-methyl-2-phenyl-, (S)-

Base Information

Chemical Name:Cyclopentanone, 2-methyl-2-phenyl-, (S)-
CAS No.:67113-14-8
Molecular Formula:C12H14O
Molecular Weight:174.243
Hs Code.:

Synonyms:

Suppliers and Price of Cyclopentanone, 2-methyl-2-phenyl-, (S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of Cyclopentanone, 2-methyl-2-phenyl-, (S)-

Chemical Property:

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclopentanone, 2-methyl-2-phenyl-, (S)-

There total 12 articles about Cyclopentanone, 2-methyl-2-phenyl-, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 591-50-4
iodobenzene

: 509323-88-0
1-methyl-2-(S)-(2-methyl-cyclopent-1-enyloxymethyl)-pyrrolidine

: 67113-14-8
(-)-(S)-2-methyl-2-phenyl cyclopentanone

: 22800-17-5
(R)-(+)-2-methyl-2-phenylcyclopentanone

Guidance literature:: iodobenzene; 1-methyl-2-(S)-(2-methyl-cyclopent-1-enyloxymethyl)-pyrrolidine; With sodium acetate; potassium carbonate; lithium chloride; palladium diacetate; In N,N-dimethyl-formamide; at 70 ℃; for 68h;

With hydrogenchloride; In N,N-dimethyl-formamide; for 0.5h; Title compound not separated from byproducts;
DOI:10.1021/ja029646c

Reference yield:

: 1120-72-5
2-Methylcyclopentanone

: 67113-14-8
(-)-(S)-2-methyl-2-phenyl cyclopentanone

Guidance literature:: Multi-step reaction with 3 steps

1.1: 4-toluenesulfonic acid monohydrate / 1 h / 0 - 20 °C

2.1: 3.90 g / HCl / toluene / 16 h / 100 °C

3.1: aq. NaOAc; K₂CO₃; LiCl / Pd(OAc)2 / dimethylformamide / 68 h / 70 °C

3.2: aq. HCl / dimethylformamide / 0.5 h

With hydrogenchloride; p-toluenesulfonic acid monohydrate; sodium acetate; potassium carbonate; lithium chloride; palladium diacetate; In N,N-dimethyl-formamide; toluene; 3.1: asymmetric Heck arylation;
DOI:10.1021/ja029646c

Reference yield:

: 76430-23-4
2-methylcyclopentanone dimethyl acetal

: 67113-14-8
(-)-(S)-2-methyl-2-phenyl cyclopentanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: 3.90 g / HCl / toluene / 16 h / 100 °C

2.1: aq. NaOAc; K₂CO₃; LiCl / Pd(OAc)2 / dimethylformamide / 68 h / 70 °C

2.2: aq. HCl / dimethylformamide / 0.5 h

With hydrogenchloride; sodium acetate; potassium carbonate; lithium chloride; palladium diacetate; In N,N-dimethyl-formamide; toluene; 2.1: asymmetric Heck arylation;
DOI:10.1021/ja029646c