1-(4-thio-beta-D-ribofuranosyl)uracil

Base Information

Chemical Name:1-(4-thio-beta-D-ribofuranosyl)uracil
CAS No.:6741-73-7
Molecular Formula:C9H12N2O5S
Molecular Weight:260.271
Hs Code.:
DSSTox Substance ID:DTXSID101317166
Nikkaji Number:J1.270.585I
Mol file:6741-73-7.mol

Synonyms:6741-73-7;4'-thiouridine;1-(4-thio-beta-D-ribofuranosyl)uracil;Uridine, 4'-thio-;1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione;1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)thiolan-2-yl]pyrimidine-2,4-dione;4'-O-Thiauridine;SCHEMBL1050440;MUSPKJVFRAYWAR-XVFCMESISA-N;DTXSID101317166;MFCD22666335;AS-47208;F12654;A848621;1-((2S,3S,4R,5S)-3,4-dihydroxy-5-(hydroxymethyl)-tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione

Suppliers and Price of 1-(4-thio-beta-D-ribofuranosyl)uracil

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione 97%
100mg
$ 526.00

Total 14 raw suppliers

Chemical Property of 1-(4-thio-beta-D-ribofuranosyl)uracil

Chemical Property:

Melting Point:195-196 °C(Solv: chloroform (67-66-3); ethanol (64-17-5))
PKA:9.39±0.10(Predicted)
PSA：140.85000
Density:1.687±0.06 g/cm3(Predicted)
LogP:-2.13530
XLogP3:-1.2
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:260.04669266
Heavy Atom Count:17
Complexity:374

Purity/Quality:

99%, ^*data from raw suppliers

1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrothiophen-2-yl)pyrimidine-2,4(1H,3H)-dione 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN(C(=O)NC1=O)C2C(C(C(S2)CO)O)O
Isomeric SMILES:C1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](S2)CO)O)O

Technology Process of 1-(4-thio-beta-D-ribofuranosyl)uracil

There total 33 articles about 1-(4-thio-beta-D-ribofuranosyl)uracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 2’,3’,5’-tri-O-benzoyl,1’-β-(4’-thio-D-ribofuranosyl)uracil

: 6741-73-7
1-(4-thio-β-D-ribofuransoyl)uracil

Guidance literature:: With methanol; ammonia; at 0 - 40 ℃; for 72h;
DOI:10.1039/d1ob02097h

Reference yield: 90.0%

: 291758-14-0
1-[2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-β-d-ribofuranosyl] uracil

: 6741-73-7
1-(4-thio-β-D-ribofuransoyl)uracil

Guidance literature:: 1-[2-O-(2,4-dimethoxybenzoyl)-3,5-O-(1,1,3,3-tetraisopropyldisiloxane-1,3-diyl)-4-thio-β-d-ribofuranosyl] uracil; With triethylamine tris(hydrogen fluoride); triethylamine; In tetrahydrofuran; at 20 ℃; for 4 - 5h;

With ammonia; In methanol; at 20 ℃;