1H-Pyrrole-2-carboxylic acid, 5,5'-[(4,6-dihydroxy-5-methyl-1,3-phenylene)bis(methylene)]bis[4-ethyl-3 -methyl-, bis(phenylmethyl) ester

Base Information

• Chemical Name: 1H-Pyrrole-2-carboxylic acid, 5,5'-[(4,6-dihydroxy-5-methyl-1,3-phenylene)bis(methylene)]bis[4-ethyl-3 -methyl-, bis(phenylmethyl) ester
• CAS No.: 675608-66-9
• Molecular Formula: C39H42N2O6
• Molecular Weight: 634.772
• Mol file: 675608-66-9.mol

Synonyms:

Chemical Property of 1H-Pyrrole-2-carboxylic acid, 5,5'-[(4,6-dihydroxy-5-methyl-1,3-phenylene)bis(methylene)]bis[4-ethyl-3 -methyl-, bis(phenylmethyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Pyrrole-2-carboxylic acid, 5,5'-[(4,6-dihydroxy-5-methyl-1,3-phenylene)bis(methylene)]bis[4-ethyl-3 -methyl-, bis(phenylmethyl) ester

There total 1 articles about 1H-Pyrrole-2-carboxylic acid, 5,5'-[(4,6-dihydroxy-5-methyl-1,3-phenylene)bis(methylene)]bis[4-ethyl-3 -methyl-, bis(phenylmethyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

2-methylbenzene-1,3-diol (608-25-3) + benzyl 5-(acetoxymethyl)-4-ethyl-3-methyl-1H-pyrrole-2-carboxylate (3750-36-5) → 4,6-bis(5-benzyloxycarbonyl-3-ethyl-4-methyl-2-pyrrolylmethyl)-1,3-dihydroxy-2-methylbenzene (675608-66-9)

Guidance literature:

With toluene-4-sulfonic acid; calcium chloride; In dichloromethane;

DOI:10.1016/j.tetlet.2006.10.053

Reference yield: 100.0%

4,6-bis(5-benzyloxycarbonyl-3-ethyl-4-methyl-2-pyrrolylmethyl)-1,3-dihydroxy-2-methylbenzene (675608-66-9) → 4,6-bis(5-carboxy-3-ethyl-4-methyl-2-pyrrolylmethyl)-1,3-dihydroxy-2-methylbenzene (675608-67-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; methanol;

DOI:10.1039/b313229n

upstream raw materials:

2-methylbenzene-1,3-diol

benzyl 5-(acetoxymethyl)-4-ethyl-3-methyl-1H-pyrrole-2-carboxylate

Downstream raw materials:

4,6-bis(5-carboxy-3-ethyl-4-methyl-2-pyrrolylmethyl)-1,3-dihydroxy-2-methylbenzene