2-morpholin-4-yl-N-(2-nitrophenyl)-2-oxoethanehydrazonoyl chloride

Base Information

Chemical Name:2-morpholin-4-yl-N-(2-nitrophenyl)-2-oxoethanehydrazonoyl chloride
CAS No.:5588-52-3
Molecular Formula:C₁₃H₁₅NO₂
Molecular Weight:217.268
Hs Code.:
DSSTox Substance ID:DTXSID40389083
Mol file:5588-52-3.mol

Synonyms:2-morpholin-4-yl-N-(2-nitrophenyl)-2-oxoethanehydrazonoyl chloride;DTXSID40389083

Suppliers and Price of 2-morpholin-4-yl-N-(2-nitrophenyl)-2-oxoethanehydrazonoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
rac-(1S,2R,8S)-14-Oxa-7-azatetracyclo[6.6.1.0~1,11~.0~2,7~]pentadeca-9,11-dien-13-one
100mg
$ 130.00

TRC
rac-(1S,2R,8S)-14-Oxa-7-azatetracyclo[6.6.1.0~1,11~.0~2,7~]pentadeca-9,11-dien-13-one
10mg
$ 45.00

Total 4 raw suppliers

Chemical Property of 2-morpholin-4-yl-N-(2-nitrophenyl)-2-oxoethanehydrazonoyl chloride

Chemical Property:

Vapor Pressure:9.2E-09mmHg at 25°C
Boiling Point:463.3°Cat760mmHg
Flash Point:234°C
PSA：29.54000
Density:1.5g/cm³
LogP:1.34290
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:312.0625326
Heavy Atom Count:21
Complexity:420

Purity/Quality:

99% ^*data from raw suppliers

rac-(1S,2R,8S)-14-Oxa-7-azatetracyclo[6.6.1.0~1,11~.0~2,7~]pentadeca-9,11-dien-13-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C(=O)C(=NNC2=CC=CC=C2[N+](=O)[O-])Cl

Technology Process of 2-morpholin-4-yl-N-(2-nitrophenyl)-2-oxoethanehydrazonoyl chloride

There total 16 articles about 2-morpholin-4-yl-N-(2-nitrophenyl)-2-oxoethanehydrazonoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 651738-07-7
1(S)-[1'-tert-butoxycarbonyl-2'(R)-piperidinyl]-3-bromo-9-oxa-8-oxobicyclo[4.3.0]nona-4,6-diene

: 884-68-4,1857-30-3,5588-52-3,5610-40-2,6704-68-3
(-)-securinine

Guidance literature:: 1(S)-[1'-tert-butoxycarbonyl-2'(R)-piperidinyl]-3-bromo-9-oxa-8-oxobicyclo[4.3.0]nona-4,6-diene; With trifluoroacetic acid; at 20 ℃; for 0.25h;

With potassium carbonate; In tetrahydrofuran; at 20 ℃; for 12h;
DOI:10.1021/ol0361251

Reference yield: 82.0%

: 1126784-60-8
(1'S,3'S,8a'R)-3'-((Z)-2-iodovinyl)-3',5',6',7',8',8a'-hexahydro-2'H,5H-spiro[furan-2,1'-indolizin]-5-one

: 884-68-4,1857-30-3,5588-52-3,5610-40-2,6704-68-3
(-)-securinine

Guidance literature:: With trans-di(μ-acetato)bis[o-(di-o-tolylphosphino)benzyl]dipalladium(II); tetrabutylammomium bromide; sodium acetate; In N,N-dimethyl acetamide; at 100 ℃; for 12h;
DOI:10.1039/b816576a

Reference yield:

: 708260-76-8
tert-butyl (2R)-2-[(2S)-2-[(Z)-4-iodo-3-butenyl]-5(2H)-oxo-2-furyl]piperidine-1-carboxylate

: 884-68-4,1857-30-3,5588-52-3,5610-40-2,6704-68-3
(-)-securinine

Guidance literature:: Multi-step reaction with 3 steps

1.1: 78 percent / PdCl₂(PPh₃)2; tetrabutylammonium bromide; PPh₃ / Na₂CO₃ / dimethylformamide / 90 °C

2.1: 64 percent / N-bromosuccinimide; benzoyl peroxide / CCl₄ / 0.75 h / Heating

3.1: trifluoroacetic acid / CHCl₃ / 20 °C

3.2: 53 percent / K₂CO₃ / tetrahydrofuran; H₂O / 0.5 h / sonication

With bis-triphenylphosphine-palladium(II) chloride; N-Bromosuccinimide; tetrabutylammomium bromide; triphenylphosphine; trifluoroacetic acid; dibenzoyl peroxide; sodium carbonate; In tetrachloromethane; chloroform; N,N-dimethyl-formamide; 1.1: Heck reaction;
DOI:10.1021/ol049455+