2-[2,5-Bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-6-(chloromethyl)oxane-3,4,5-triol

Base Information

• Chemical Name: 2-[2,5-Bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-6-(chloromethyl)oxane-3,4,5-triol
• CAS No.: 40631-75-2
• Molecular Formula: C₁₂H₁₉Cl₃O₈
• Molecular Weight: 397.637
• UNII: CGG2B0M3MW
• Nikkaji Number: J589.547B
• Mol file: 40631-75-2.mol

Synonyms:40631-75-2;CGG2B0M3MW;1',6,6'-Trichlorosucrose;6,1',6'-Trichlorosucrose;2-[2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-6-(chloromethyl)oxane-3,4,5-triol;NSC-297293;1',6,6'-Trichloro-1',6,6'-trideoxysucrose;6,1',6'-Trichloro-6,1',6'-trideoxysucrose;(2R,3R,4S,5S,6S)-2-[(2R,3S,4S,5S)-2,5-bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-6-(chloromethyl)oxane-3,4,5-triol;(2R,3R,4S,5S,6S)-2-(((2R,3S,4S,5S)-2,5-Bis(chloromethyl)-3,4-dihydroxytetrahydrofuran-2-yl)oxy)-6-(chloromethyl)tetrahydro-2H-pyran-3,4,5-triol;UNII-CGG2B0M3MW;SUCRALOSE IMPURITY B [EP IMPURITY];1,6-Dichloro-1,6-dideoxy-beta-D-fructofuranosyl 6-chloro-6-deoxy-alpha-D-glucopyranoside;alpha-D-Glucopyranoside, 1,6-dichloro-1,6-dideoxy-beta-D-fructofuranosyl 6-chloro-6-deoxy-;.ALPHA.-D-GLUCOPYRANOSIDE, 1,6-DICHLORO-1,6-DIDEOXY-.BETA.-D-FRUCTOFURANOSYL 6-CHLORO-6-DEOXY-;1,6-DICHLORO-1,6-DIDEOXY-.BETA.-D-FRUCTOFURANOSYL 6-CHLORO-6-DEOXY-.ALPHA.-D-GLUCOPYRANOSIDE

Chemical Property of 2-[2,5-Bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-6-(chloromethyl)oxane-3,4,5-triol

Chemical Property:

• Vapor Pressure: 5.63E-19mmHg at 25°C
• Boiling Point: 638.2°Cat760mmHg
• Flash Point: 339.8°C
• PSA: 128.84000
• Density: 1.69g/cm³
• LogP: -1.65610
• XLogP3: -1.5
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 5
• Exact Mass: 396.014551
• Heavy Atom Count: 23
• Complexity: 405

Purity/Quality:

99% ^*data from raw suppliers

1’,6,6’-TrichloroSucrose ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)OC2(C(C(C(O2)CCl)O)O)CCl)O)O)O)Cl
• Isomeric SMILES: C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CCl)O)O)CCl)O)O)O)Cl
• Uses: 1',6,6'-Trichloro SucroseI can be used in the method for the purification of Sucralose. Polar impurities may be removed with methanol and non-polar impurities may be removed by using dichloromethane-water-MTBE. Sucralose (S692500) impurity. It is used in the method for the purification of Sucralose. Polar impurities may be removed with methanol and non-polar impurities may be removed by using dichloromethane-water-MTBE.

Technology Process of 2-[2,5-Bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-6-(chloromethyl)oxane-3,4,5-triol

There total 1 articles about 2-[2,5-Bis(chloromethyl)-3,4-dihydroxyoxolan-2-yl]oxy-6-(chloromethyl)oxane-3,4,5-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl-6-chloro-6-deoxy-α-D-glucopyranoside (40631-75-2)

Guidance literature:

6, Na/Me.;

DOI:10.1016/S0008-6215(00)81662-6