Diethyl [hydroxy(2-methoxyphenyl)methyl]phosphonate

Base Information

Chemical Name:Diethyl [hydroxy(2-methoxyphenyl)methyl]phosphonate
CAS No.:67691-77-4
Molecular Formula:C₁₂H₁₉O₅P
Molecular Weight:274.254
Hs Code.:
DSSTox Substance ID:DTXSID00573688
Nikkaji Number:J847.122C

Synonyms:67691-77-4;Diethyl [hydroxy(2-methoxyphenyl)methyl]phosphonate;DTXSID00573688

Suppliers and Price of Diethyl [hydroxy(2-methoxyphenyl)methyl]phosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Diethyl [hydroxy(2-methoxyphenyl)methyl]phosphonate

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:274.09701070
Heavy Atom Count:18
Complexity:274

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOP(=O)(C(C1=CC=CC=C1OC)O)OCC

Technology Process of Diethyl [hydroxy(2-methoxyphenyl)methyl]phosphonate

There total 2 articles about Diethyl [hydroxy(2-methoxyphenyl)methyl]phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 762-04-9
phosphonic acid diethyl ester

: 135-02-4
ortho-anisaldehyde

: 67691-77-4,1244759-39-4,169172-45-6
diethyl 1-hydroxy-1-(2’-methoxyphenyl)methyl phosphonate

Guidance literature:: With (Me₂NCH₂CH₂N{CH₂-(2-OC₆H₂^tBu₂-3,5)}₂)Yb[(TMS)₂NC(NCy)₂]; In neat (no solvent); at 20 ℃; for 0.0833333h; Inert atmosphere; Schlenk technique;
DOI:10.1016/j.jorganchem.2014.12.021

Reference yield: 92.0%

Diethyl phosphonate: 762-04-9,123-22-8
Diethyl phosphonate

: 135-02-4
ortho-anisaldehyde

: 67691-77-4,1244759-39-4,169172-45-6
diethyl 1-hydroxy-1-(2’-methoxyphenyl)methyl phosphonate

Guidance literature:: Diethyl phosphonate; With [(Me₃Si)₂N]₃La(μ-Cl)Li(THF)₃; In toluene; for 0.166667h; Inert atmosphere;

ortho-anisaldehyde; In toluene; at 25 ℃; for 0.0833333h; Inert atmosphere;
DOI:10.1021/jo101743e