2,6-Dichloro-3,5-diphenylpyrazine

Base Information

Chemical Name:2,6-Dichloro-3,5-diphenylpyrazine
CAS No.:67714-55-0
Molecular Formula:C16H10Cl2N2
Molecular Weight:301.175
Hs Code.:
DSSTox Substance ID:DTXSID90497905
Nikkaji Number:J900.091G

Synonyms:2,6-Dichloro-3,5-diphenylpyrazine;67714-55-0;SCHEMBL10444909;DTXSID90497905

Suppliers and Price of 2,6-Dichloro-3,5-diphenylpyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2,6-Dichloro-3,5-diphenylpyrazine

Chemical Property:

XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:300.0221037
Heavy Atom Count:20
Complexity:273

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(N=C(C(=N2)C3=CC=CC=C3)Cl)Cl

Technology Process of 2,6-Dichloro-3,5-diphenylpyrazine

There total 5 articles about 2,6-Dichloro-3,5-diphenylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 78754-70-8
3-chloro-2,6-diphenylpyrazine 4-oxide

: 67714-55-0
3,5-dichloro-2,6-diphenylpyrazine

Guidance literature:: With trichlorophosphate; for 0.5h; Heating;

Reference yield: 60.0%

: 33837-38-6
1-hydroxy-3,5-diphenyl-1H-pyrazin-2-one

: 67714-55-0
3,5-dichloro-2,6-diphenylpyrazine

: 33837-33-1
6-chloro-3,5-diphenyl-1H-pyrazin-2-one

Guidance literature:: With POCl₂; for 20h; Heating;
DOI:10.1039/a704415a

Reference yield:

: 25827-94-5
2,6-diphenylpyrazine

: 67714-55-0
3,5-dichloro-2,6-diphenylpyrazine

Guidance literature:: Multi-step reaction with 4 steps

1: 82 percent / 90percent H₂O₂, maleic anhydride / CHCl₃ / 1.) room temperature, overnight; 2.) reflux, 4 h

2: 89 percent / POCl₃ / 0.5 h / Heating

3: 96 percent / 90percent H₂O₂, maleic anhydride / CHCl₃ / 1.) room temperature, overnight; 2.) reflux, 5 h

4: 85 percent / POCl₃ / 0.5 h / Heating

With maleic anhydride; dihydrogen peroxide; trichlorophosphate; In chloroform;