2,5-Dichlorobenzenesulfonohydrazide

Base Information

• Chemical Name: 2,5-Dichlorobenzenesulfonohydrazide
• CAS No.: 6775-66-2
• Molecular Formula: C6H6Cl2N2O2S
• Molecular Weight: 241.098
• Hs Code.: 2935009090
• European Community (EC) Number: 662-155-6
• DSSTox Substance ID: DTXSID90366187
• Wikidata: Q82151306
• Mol file: 6775-66-2.mol

Synonyms:2,5-dichlorobenzenesulfonohydrazide;6775-66-2;SCHEMBL6259655;DTXSID90366187;BBL016815;MFCD00159279;STK435219;AKOS003270575;2,5-dichlorobenzene-1-sulfonohydrazide;LS-01219;2,5-DICHLOROBENZENESULFONIC HYDRAZIDE;A915711

Chemical Property of 2,5-Dichlorobenzenesulfonohydrazide

Chemical Property:

• PSA: 80.57000
• LogP: 3.31740
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 239.9527040
• Heavy Atom Count: 13
• Complexity: 264

Purity/Quality:

97% ^*data from raw suppliers

2,5-Dichlorobenzenesulfonohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1Cl)S(=O)(=O)NN)Cl

Technology Process of 2,5-Dichlorobenzenesulfonohydrazide

There total 1 articles about 2,5-Dichlorobenzenesulfonohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

2,5-dichlorobenzenesulphonyl chloride (5402-73-3) → 2,5-dichlorobenzenesulfonylhydrazide (6775-66-2)

Guidance literature:

With hydrazine hydrate; In ethanol; 1) heat 2) room temperature, 1 h;

Reference yield: 91.0%

1-methyl-2(1H)-quinoxalinone (6479-18-1) + 2,5-dichlorobenzenesulfonylhydrazide (6775-66-2) + phenylacetylene (536-74-3) → (Z)-3-(2-((2,5-dichlorophenyl)sulfonyl)-1-phenylvinyl)-1-methylquinoxalin-2(1H)-one

Guidance literature:

With tert.-butylhydroperoxide; copper(II) bis(trifluoromethanesulfonate); In 1,2-dichloro-ethane; at 80 ℃; for 4h; regioselective reaction;

DOI:10.1002/adsc.202001182

Reference yield: 87.0%

2,5-dichlorobenzenesulfonylhydrazide (6775-66-2) + 6,6-dimethyl-1-phenyl-1,5,6,7-tetrahydro-4H-indazol-4-one (43102-70-1) → (E)-2,6-dichloro-N'-(6,6-dimethyl-1-phenyl-1,5,6,7-tetrahydro-4H&No.x;FFFE;indazol-4-ylidene)benzenesulfonohydrazide

Guidance literature:

With acetic acid; In ethanol; for 2h; Reflux;

DOI:10.1016/j.bioorg.2019.103410

upstream raw materials:

2,5-dichlorobenzenesulphonyl chloride

Downstream raw materials:

C₁₃H₉Cl₂N₃O₄S

C₁₃H₁₀Cl₂N₂O₃S

C₁₃H₁₂Cl₂N₂O₄S₂

glyoxylic acid 2,5-dichlorobenzenesulfonylhydrazone