Benzenamine, N-[2-(diphenylphosphino)phenyl]-2,6-dimethyl-

Base Information

• Chemical Name: Benzenamine, N-[2-(diphenylphosphino)phenyl]-2,6-dimethyl-
• CAS No.: 678172-40-2
• Molecular Formula: C26H24NP
• Molecular Weight: 381.457
• DSSTox Substance ID: DTXSID30477721
• Nikkaji Number: J2.026.676G
• Wikidata: Q82310592

Synonyms:678172-40-2;Benzenamine, N-[2-(diphenylphosphino)phenyl]-2,6-dimethyl-;N-(2-(Diphenylphosphino)phenyl)-2,6-dimethylaniline;N-(2-diphenylphosphanylphenyl)-2,6-dimethylaniline;SCHEMBL3947196;DTXSID30477721;N-[2-(Diphenylphosphino)phenyl]-2,6-dimethylbenzenamine

Chemical Property of Benzenamine, N-[2-(diphenylphosphino)phenyl]-2,6-dimethyl-

Chemical Property:

• XLogP3: 6.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 381.164636767
• Heavy Atom Count: 28
• Complexity: 425

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C(=CC=C1)C)NC2=CC=CC=C2P(C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of Benzenamine, N-[2-(diphenylphosphino)phenyl]-2,6-dimethyl-

There total 5 articles about Benzenamine, N-[2-(diphenylphosphino)phenyl]-2,6-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N-(2-fluorophenyl)-2,6-dimethylaniline + potassium diphenylphosphine (15475-27-1,4346-39-8) → N-[2-(diphenylphosphino)phenyl]-2,6-dimethylaniline (678172-40-2)

Guidance literature:

In tetrahydrofuran; at 180 ℃; for 1h; microwave irradiation;

DOI:10.1021/jo8001497

Reference yield: 74.0%

2-bromo-N-(2,6-dimethylphenyl)aniline (1163303-71-6) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → N-[2-(diphenylphosphino)phenyl]-2,6-dimethylaniline (678172-40-2)

Guidance literature:

2-bromo-N-(2,6-dimethylphenyl)aniline; With n-butyllithium; In diethyl ether; hexane; at -35 - 20 ℃;

chloro-diphenylphosphine; In diethyl ether; hexane; water; at -35 - 20 ℃;

DOI:10.1039/c0dt00327a

Reference yield:

2,6-dimethylaniline (87-62-7) → N-[2-(diphenylphosphino)phenyl]-2,6-dimethylaniline (678172-40-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether; sodium t-butanolate / toluene / 72 h / 95 °C / Inert atmosphere; sealed

2.1: n-butyllithium / diethyl ether; hexane / -35 - 20 °C

2.2: -35 - 20 °C

With n-butyllithium; palladium diacetate; bis[2-(diphenylphosphino)phenyl] ether; sodium t-butanolate; In diethyl ether; hexane; toluene;

DOI:10.1039/c0dt00327a

upstream raw materials:

potassium diphenylphosphine

2-bromo-N-(2,6-dimethylphenyl)aniline

chloro-diphenylphosphine

1-Bromo-2-iodobenzene

Downstream raw materials:

[N-(2-diphenylphosphinophenyl)-2,6-dimethylanilide]Li(THF)2

(N-(2-diphenylphosphinophenyl)-2,6-dimethylaniline(-1H))Lu(CH₂SiMe₃)2(THF)*(hexane)

(N-(2-diphenylphosphinophenyl)-2,6-dimethylaniline(-1H))Y(CH₂SiMe₃)2(THF)2

(N-(2-diphenylphosphinophenyl)-2,6-dimethylaniline(-1H))Tm(CH₂SiMe₃)2(THF)

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 678172-40-2 Benzenamine, N-[2-(diphenylphosphino)phenyl]-2,6-dimethyl-

Send

Send

Metric Ton KG G Pound L ML

Send

Send