1-(2-Methylpyrimidin-4-yl)propan-1-one

Base Information

Chemical Name:1-(2-Methylpyrimidin-4-yl)propan-1-one
CAS No.:67860-39-3
Molecular Formula:C8H10N2O
Molecular Weight:150.17800
Hs Code.:
DSSTox Substance ID:DTXSID40522534
Wikidata:Q82387883

Synonyms:1-(2-Methylpyrimidin-4-yl)propan-1-one;67860-39-3;SCHEMBL11451174;DTXSID40522534;AKOS017413702

Suppliers and Price of 1-(2-Methylpyrimidin-4-yl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-(2-Methylpyrimidin-4-yl)propan-1-one

Chemical Property:

Boiling Point:237.4±13.0 °C(Predicted)
PKA:-0.75±0.31(Predicted)
PSA：42.85000
Density:1.071±0.06 g/cm3(Predicted)
LogP:1.37770
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:150.079312947
Heavy Atom Count:11
Complexity:147

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)C1=NC(=NC=C1)C

Technology Process of 1-(2-Methylpyrimidin-4-yl)propan-1-one

There total 5 articles about 1-(2-Methylpyrimidin-4-yl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 89967-08-8
1-(2-Methyl-pyrimidin-4-yl)-propan-1-one oxime

: 67860-39-3
2-methyl-4-propionyl-pyrimidine

Guidance literature:: With hydrogenchloride; 2-oxo-propionic acid; In ethanol; for 6h; Heating;

Reference yield:

: 89967-02-2
2-Methyl-4-propyl-pyrimidine

: 67860-39-3
2-methyl-4-propionyl-pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / propyl nitrite, HCl / ethanol / 2 h / Ambient temperature

2: 40 percent / pyruvic acid, conc. HCl / aq. ethanol / 6 h / Heating

With hydrogenchloride; n-propyl nitrite; 2-oxo-propionic acid; In ethanol;

Reference yield:

: 3249-68-1
ethyl butyroyl acetate

: 67860-39-3
2-methyl-4-propionyl-pyrimidine

Guidance literature:: Multi-step reaction with 5 steps

1: 61 percent / 1.) sodium methoxide / 1.) methanol, rt., 12 h; 2.) 120 deg C, 20 mmHg, 2 h

2: 79 percent / phosphoryl chloride / 3 h / Heating

3: 88 percent / zinc/satd. aq. NaCl/5percent ammonia / benzene / 12 h / Heating

4: 60 percent / propyl nitrite, HCl / ethanol / 2 h / Ambient temperature

5: 40 percent / pyruvic acid, conc. HCl / aq. ethanol / 6 h / Heating

With hydrogenchloride; ammonium hydroxide; n-propyl nitrite; sodium methylate; 2-oxo-propionic acid; sodium chloride; zinc; trichlorophosphate; In ethanol; benzene;