(5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone

Base Information

Chemical Name:(5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone
CAS No.:68100-95-8
Molecular Formula:C₁₀H₇ClN₂O₂
Molecular Weight:222.631
Hs Code.:
DSSTox Substance ID:DTXSID40497591
Wikidata:Q82347239
Mol file:68100-95-8.mol

Synonyms:68100-95-8;4-(5-CHLORO-2-HYDROXYBENZOYL)PYRAZOLE;(5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone;DTXSID40497591;AKOS000275930

Suppliers and Price of (5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Heterocyclics
(5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone 96%
1g
$ 250.00

Heterocyclics
(5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone 96%
5g
$ 750.00

American Custom Chemicals Corporation
(5-CHLORO-2-HYDROXYPHENYL)(1H-PYRAZOL-4-YL)METHANONE 95.00%
5MG
$ 505.78

Total 1 raw suppliers

Chemical Property of (5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone

Chemical Property:

Melting Point:180 °C(Solv: ethanol (64-17-5))
Boiling Point:433.4±35.0 °C(Predicted)
PKA:6.99±0.43(Predicted)
PSA：65.98000
Density:1.489±0.06 g/cm3(Predicted)
LogP:1.99970
XLogP3:2.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:222.0196052
Heavy Atom Count:15
Complexity:250

Purity/Quality:: (5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1Cl)C(=O)C2=CNN=C2)O

Technology Process of (5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone

There total 4 articles about (5-Chloro-2-hydroxyphenyl)(1H-pyrazol-4-yl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 72164-97-7
6-Chloro-4-oxo-4H-chromene-3-carbaldehyde oxime

: 68100-95-8
(5-chloro-2-hydroxy-phenyl)-(1H-pyrazol-4-yl)-methanone

Guidance literature:: With hydrazine hydrochloride; In ethanol; for 15h; Heating;

Reference yield: 58.0%

: 88021-73-2
6-Chloro-3-[1,3]dioxolan-2-yl-chromen-4-one

: 68100-95-8
(5-chloro-2-hydroxy-phenyl)-(1H-pyrazol-4-yl)-methanone

Guidance literature:: With hydrazine hydrate; In pyridine; for 5h; Heating;

Reference yield:

: 42248-31-7
6-Chloro-4-oxo-4H-chromene-3-carbaldehyde

: 68100-95-8
(5-chloro-2-hydroxy-phenyl)-(1H-pyrazol-4-yl)-methanone

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / toluene-p-sulphonic acid / benzene / 8 h / Heating

2: 58 percent / hydrazine hydrate / pyridine / 5 h / Heating

With toluene-4-sulfonic acid; hydrazine hydrate; In pyridine; benzene;